ReviewCells2021
Chronic Diabetic Wounds and Their Treatment with Skin Substitutes.
Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
154 citing papers in PubMed, 2 syntheses or guidelines pooled it, 310 citations in OpenAlex.
- Clinical Evidence of Traditional Medicines in Modulating the Immune Response and Diabetic Wound Healing.Current topics in medicinal chemistry · 2026Pooled it
- The diabetic neuropathy and bone mineral density in type 2 diabetes mellitus: a cross-sectional and meta-analytic study.Clinical and experimental medicine · 2025Pooled it
- Review
- [Expert consensus on the application of bone cement in the treatment of diabetic wounds (2026 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- A Tissue-Homologous Keratin-PBA Hydrogel Integrating Rationally Designed Nanomicelles Enables Microenvironment-Adaptive Repair of Chronic Diabetic Wounds.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Review
- Multifunctional Hydrogels for Diabetic Wound Healing: Design Strategies and Microenvironmental Remodeling Mechanisms.Gels (Basel, Switzerland) · 2026Review
- Black Sea-Derived Biomaterials for Wound-Healing Applications.International journal of molecular sciences · 2026Article
- TeSe nanoparticle-integrated exosomes for accelerated diabetic Pressure ulcer healing via NIR-II triggered synergy.Biomaterials and biosystems · 2026Article
- Enhanced functional mitochondrial donation through glucose-responsive antioxidant microcarrier-engineered native-like MSCs accelerates diabetic wound healing.Materials today. Bio · 2026Article
- Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions.International wound journal · 2026Review
- Procyanidin capsules attenuate PI3K/AKT-mediated mitochondrial dysfunction and accelerate skin wound healing in diabetic mice.Materials today. Bio · 2026Article
- Mitophagy-activating nanozyme hydrogel for enhanced diabetic wound healing.Materials today. Bio · 2026Article
- Sprayable Hydrogel Dressings in Wound-Healing Applications.Bioengineering (Basel, Switzerland) · 2026Review
- A platelet-rich plasma-loaded chitosan-based hydrogel for promoting type 2 diabetes wound healing.iScience · 2026Article
- Dysregulated Repair in Aging and Disease: Extracellular Vesicles as an Emerging Protective Strategy.Cells · 2026Review
- Application of 3D-Bioprinting in Treatment of Chronic Wounds: A Review.Life (Basel, Switzerland) · 2026Review
- Engineered catechol-based composite materials for diabetic wound healing.Materials today. Bio · 2026Review
- Sustained-release CGRP microspheres accelerate diabetic wound healing by synergistically promoting neurovascular regeneration through modulation of macrophage and endothelial cell functions.Materials today. Bio · 2026Article
- Endothelial ferroptosis: a novel mechanism and therapeutic target in diabetic microvascular complications.Molecular medicine (Cambridge, Mass.) · 2026Review
94 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
With the global prevalence of type 2 diabetes mellitus steeply rising, instances of chronic, hard-healing, or non-healing diabetic wounds and ulcers are predicted to increase. The growing understanding of healing and regenerative mechanisms has elucidated critical regulators of this process, including key cellular and humoral components. Despite this, the management and successful treatment of diabetic wounds represents a significant therapeutic challenge. To this end, the development of novel therapies and biological dressings has gained increased interest. Here we review key differences between normal and chronic non-healing diabetic wounds, and elaborate on recent advances in wound healing treatments with a particular focus on biological dressings and their effect on key wound healing pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.