Evidence map›Paper›PMID 33804176›Full record

ArticlePharmaceutics2021

The Effect of a TLR4 Agonist/Cationic Liposome Adjuvant on Varicella-Zoster Virus Glycoprotein E Vaccine Efficacy: Antigen Presentation, Uptake, and Delivery to Lymph Nodes.

Seo Ri Wui, Ara Ko, Ji In Ryu, Eojin Sim, Soo Jeong Lim, Shin Ae Park, Kwang Sung Kim, Ha Kim, Hyewon Youn, Na Gyong Lee

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Seo Ri WuiDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.
Ara KoDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.ORCID 0000-0002-5348-6556
Ji In RyuDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.
Eojin SimDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.
Soo Jeong LimDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.
Shin Ae ParkR & D Center, EyeGene, Goyang 10551, Korea.
Kwang Sung KimDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.
Ha KimCancer Research Institute, College of Medicine, Seoul National University, Seoul 03080, Korea.
Hyewon YounCancer Research Institute, College of Medicine, Seoul National University, Seoul 03080, Korea.
Na Gyong LeeDepartment of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.ORCID 0000-0001-6842-9995
Sejong University · KRSeoul National University · KRKim's Eye Hospital · KR

Funding

Korean Health Technology R&D Project HI14C2664Ministry of Food and Drug Safety of Republic of Korea 20172MFDS284Ministry of Health & Welfare, Republic of Korea HI13C0826
6 · The paper itself

Abstract

Adjuvant CIA09, composed of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP)-based cationic liposomes and the toll-like receptor 4 agonist de-

Indexed as

antigen delivery to lymph nodescationic liposomescellular antigen uptakeCIA09TLR4 agonist de-O-acylated lipooligosaccharidesvaccine adjuvantVZV gE antigen

Identifiers

PMID33804176
PMCPMC8001429
OpenAlexW3138162244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.