Evidence map›Paper›PMID 33804115›Full record

ArticleBiomedicines2021

Valine-279 Deletion-Mutation on Arginine Vasopressin Receptor 2 Causes Obstruction in G-Protein Binding Site: A Clinical Nephrogenic Diabetes Insipidus Case and Its Sub-Molecular Pathogenic Analysis.

Ming-Chun Chen, Yu-Chao Hsiao, Chun-Chun Chang, Sheng-Feng Pan, Chih-Wen Peng, Ya-Tzu Li, Cheng-Der Liu, Je-Wen Liou, Hao-Jen Hsu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ming-Chun ChenDepartment of Pediatrics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.ORCID 0000-0003-0910-1185
Yu-Chao HsiaoDepartment of Pediatrics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.ORCID 0000-0002-4142-6433
Chun-Chun ChangDepartment of Laboratory Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.
Sheng-Feng PanDepartment of Biochemistry, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.
Chih-Wen PengDepartment of Life Science, College of Science and Engineering, National Dong Hwa University, Hualien 974301, Taiwan.
Ya-Tzu LiDepartment of Biochemistry, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.
Cheng-Der LiuDepartment of Life Science, College of Science and Engineering, National Dong Hwa University, Hualien 974301, Taiwan.
Je-Wen LiouDepartment of Biochemistry, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.ORCID 0000-0002-6181-7263
Hao-Jen HsuDepartment of Biochemistry, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.ORCID 0000-0001-6096-7481
Tzu Chi University · TWNational Dong Hwa University · TWTzu Chi Foundation · TW

Funding

Tzu Chi Foundation TCIRP109003
6 · The paper itself

Abstract

Congenital nephrogenic diabetes insipidus (CNDI) is a genetic disorder caused by mutations in arginine vasopressin receptor 2 (

Indexed as

AVPR2CNDImolecular dynamics simulationstructural analysisV279 deletion–mutation

Identifiers

PMID33804115
PMCPMC8002004
OpenAlexW3138853836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.