Evidence map›Paper›PMID 33804083›Full record

ArticleMolecules (Basel, Switzerland)2021

Optimization of Pressurized Liquid Extraction of Lycopodiaceae Alkaloids Obtained from Two

Aleksandra Dymek, Jarosław Widelski, Krzysztof Kamil Wojtanowski, Paulina Płoszaj, Rostyslav Zhuravchak, Tomasz Mroczek

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Journal of clinical medicine · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Aleksandra DymekIndependent Laboratory of Chemistry of Natural Products, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
Jarosław WidelskiDepartment of Pharmacognosy, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.ORCID 0000-0003-3154-9138
Krzysztof Kamil WojtanowskiDepartment of Pharmacognosy, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
Paulina PłoszajIndependent Laboratory of Chemistry of Natural Products, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
Rostyslav ZhuravchakRivnenskyi Nature Reserve, Natural Boundary "Rozvylka", 34500 Sarny, Rivne Region, Ukraine.
Tomasz MroczekIndependent Laboratory of Chemistry of Natural Products, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.ORCID 0000-0002-5267-7182
Medical University of Lublin · PLRivne State University of Humanities · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkaloids of the Lycopodiaceae family are of great interest to researchers due to their numerous properties and wide applications in medicine. They play a very important role mainly due to their potent antioxidant, antidepressant effects and a reversible ability to inhibit acetylcholinesterase (AChE) enzyme activity. This property is of immense importance due to the growing problem of an increasing number of patients with neurodegenerative diseases in developed countries and a lack of effective and efficient treatment for them. Numerous studies have shown that Lycopodiaceae alkaloids are a rich source of AChE inhibitors. In the obtaining of new therapeutic phytochemicals from plant material, the extraction process and its efficiency is crucial. Therefore, the aim of this work was to optimize the conditions of modern PLE to obtain bioactive alkaloids from two

Indexed as

AcetylcholinesteraseAlkaloidsAntioxidantsCholinesterase InhibitorsChromatography, High Pressure LiquidLycopodiaceaeLycopodiumMass SpectrometryPlant ExtractsSolid Phase ExtractionAcetylcholinesteraseAlkaloidsAntioxidantsCholinesterase InhibitorsPlant ExtractsHPLC/ESI-QTOF–MSLycopodium alkaloidsLycopodium annotinum L.Lycopodium clavatum L.pressurized liquid extractionsolid-phase extraction

Identifiers

PMID33804083
PMCPMC7998095
OpenAlexW3137466861

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.