Evidence map›Paper›PMID 33804015›Full record

Observational studyNutrients2021

Current Management of Hyperkalemia in Non-Dialysis CKD: Longitudinal Study of Patients Receiving Stable Nephrology Care.

Silvio Borrelli, Luca De Nicola, Roberto Minutolo, Giuseppe Conte, Paolo Chiodini, Adamasco Cupisti, Domenico Santoro, Vincenzo Calabrese, Domenico Giannese, Carlo Garofalo and 6 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Silvio BorrelliNephrology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Luca De NicolaNephrology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-8532-0182
Roberto MinutoloNephrology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giuseppe ConteNephrology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Paolo ChiodiniMedical Statistics Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Adamasco CupistiDepartment of Clinical and Experimental Medicine, University of Pisa, 56121 Pisa, Italy.ORCID 0000-0002-8995-936X
Domenico SantoroUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, University of Messina, 98168 Messina, Italy.
Vincenzo CalabreseUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, University of Messina, 98168 Messina, Italy.
Domenico GianneseDepartment of Clinical and Experimental Medicine, University of Pisa, 56121 Pisa, Italy.
Carlo GarofaloNephrology Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Michele ProvenzanoNephrology Unit, "Magna Graecia", Department of Health Sciences, "Magna Graecia", University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-2168-702X
Vincenzo BellizziNephrology Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84135 Salerno, Italy.ORCID 0000-0001-9374-0152
Luca ApicellaNephrology Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84135 Salerno, Italy.ORCID 0000-0002-8140-9136
Giorgina Barbara PiccoliNephrology Unit, San Luigi Hospital-University of Torino, 10100 Torino, Italy.ORCID 0000-0002-2632-4009
Massimo TorreggianiNephrology Unit, Centre Hospitalier Le Mans, 72037 Le Mans, France.ORCID 0000-0002-5561-948X
Biagio Raffaele Di IorioDivision of Nephrology, Moscati Hospital, 83100 Avellino, Italy.ORCID 0000-0003-2779-4181
University of Campania "Luigi Vanvitelli" · ITCentre Hospitalier du Mans · FROspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversity of Messina · ITUniversity of Pisa · ITAzienda Ospedaliera S.Giuseppe Moscati · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNo study has explored the limitations of current long-term management of hyperkalemia (HK) in outpatient CKD clinics.

methodsWe evaluated the association between current therapeutic options and control of serum K (sK) during 12-month follow up in ND-CKD patients stratified in four groups by HK (sK ≥ 5.0 mEq/L) at baseline and month 12: Absent (no-no), Resolving (yes-no), New Onset (no-yes), Persistent (yes-yes).

resultsWe studied 562 patients (age 66.2 ± 14.5 y; 61% males; eGFR 39.8 ± 21.8 mL/min/1.73 m

conclusionsThis observational study discloses that one-third of ND-CKD patients under nephrology care remain with or develop HK during a 12-month period despite low K intake and increased use of sK-lowering drugs.

Indexed as

AgedBicarbonatesBuffersDiureticsFemaleFollow-Up StudiesHumansHyperkalemiaLongitudinal StudiesMaleMiddle AgedNephrologyPotassiumRenal Insufficiency, ChronicBicarbonatesBuffersDiureticsPotassiumCKDdiethyperkalemiapotassiumRAASI

Identifiers

PMID33804015
PMCPMC8000881
OpenAlexW3138419622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.