Evidence map›Paper›PMID 33803994›Full record

ArticleInternational journal of molecular sciences2021

Glyphosate and AMPA Induce Alterations in Expression of Genes Involved in Chromatin Architecture in Human Peripheral Blood Mononuclear Cells (In Vitro).

Ewelina Woźniak, Edyta Reszka, Ewa Jabłońska, Jaromir Michałowicz, Bogumiła Huras, Bożena Bukowska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ewelina WoźniakDepartment of Biophysics of Environmental Pollution, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-4755-425X
Edyta ReszkaDepartment of Molecular Genetics and Epigenetics, Nofer Institute of Occupational Medicine, Teresy 8, 91-348 Lodz, Poland.ORCID 0000-0003-2153-4864
Ewa JabłońskaDepartment of Molecular Genetics and Epigenetics, Nofer Institute of Occupational Medicine, Teresy 8, 91-348 Lodz, Poland.ORCID 0000-0002-3946-3964
Jaromir MichałowiczDepartment of Biophysics of Environmental Pollution, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-7293-596X
Bogumiła HurasŁukasiewicz Research Network, Institute of Industrial Organic Chemistry, Annopol 6 Str, 03-236 Warsaw, Poland.
Bożena BukowskaDepartment of Biophysics of Environmental Pollution, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0003-3044-2953
University of Łódź · PLNofer Institute of Occupational Medicine · PLInstitute of Industrial Organic Chemistry · PL

Funding

Polish Ministry of Science and Higher Education B1811000001802.02University of Łódź B16/17 000000191.01
6 · The paper itself

Abstract

We have determined the effect of glyphosate and aminomethylphosphonic acid (AMPA) on expression of genes involved in chromatin architecture in human peripheral blood mononuclear cells (PBMCs). The cells were incubated with glyphosate and AMPA in the concentrations ranging from 0.5 to 100 μM and from 0.5, to 250 μM, respectively. The expression profile of the following genes by quantitative Real-Time PCR was evaluated: Genes involved in the DNA methylation (

Indexed as

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidChromatinDioxygenasesDNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDNA MethylationDNA Methyltransferase 3AEpigenesis, GeneticGene Expression RegulationGlycineGlyphosateHerbicidesHistocompatibility AntigensHistone DeacetylasesHistone-Lysine N-MethyltransferaseHumansalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidChromatinDioxygenasesDNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT1 protein, humanDNMT3A protein, humanEHMT2 protein, humanGlycineGlyphosateHDAC5 protein, humanHerbicidesHistocompatibility AntigensHistone DeacetylasesHistone-Lysine N-MethyltransferaseReactive Oxygen SpeciesTET3 protein, humanAMPAchromatin structureepigeneticsglyphosatehuman peripheral blood mononuclear cells

Identifiers

PMID33803994
PMCPMC7998550
OpenAlexW3138041410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.