Evidence map›Paper›PMID 33803890›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis, Antifungal Activity, and 3D-QSAR Study of Novel Nopol-Derived 1,3,4-Thiadiazole-Thiourea Compounds.

Ming Chen, Wen-Gui Duan, Gui-Shan Lin, Zhong-Tian Fan, Xiu Wang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Antimicrobial Activity of 1,3,4-Thiadiazole Derivatives.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ming ChenSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Wen-Gui DuanSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Gui-Shan LinSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Zhong-Tian FanSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.ORCID 0000-0002-3320-3168
Xiu WangSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.

Funding

National Natural Science Foundation of China No. 31870556
6 · The paper itself

Abstract

A series of novel nopol derivatives bearing the 1,3,4-thiadiazole-thiourea moiety were designed and synthesized by multi-step reactions in search of potent natural product-based antifungal agents. Their structures were confirmed by FT-IR, NMR, ESI-MS, and elemental analysis. Antifungal activity of the target compounds was preliminarily evaluated by in vitro methods against

Indexed as

Antifungal AgentsBridged Bicyclo CompoundsDrug DesignFungiFungicides, IndustrialMicrobial Sensitivity TestsModels, MolecularMolecular StructureQuantitative Structure-Activity RelationshipStatic ElectricityThiadiazolesThioureaAntifungal AgentsBridged Bicyclo CompoundsFungicides, IndustrialnopolThiadiazolesThiourea1,3,4-thiadiazole3D-QSARantifungal activitynopolthioureaβ-pinene

Identifiers

PMID33803890
PMCPMC8003325

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.