Evidence map›Paper›PMID 33803880›Full record

ArticleBiosensors2021

Subtle Application of Electrical Field-Induced Lossy Mode Resonance to Enhance Performance of Optical Planar Waveguide Biosensor.

Yu-Cheng Lin, Liang-Yü Chen

Abstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Smart green CQD@SiONanoscale advances · 2023
    Article
  2. Review
  3. Article
  4. High-Sensitivity PtSeBiosensors · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yu-Cheng LinElectronic Engineering Department, Ming-Chung University, Taoyuan 33348, Taiwan.ORCID 0000-0001-9124-8092
Liang-Yü ChenBiotechnology Department, Ming-Chung University, Taoyuan 33348, Taiwan.ORCID 0000-0002-2981-1945

Funding

Ministry of Science and Technology, Taiwan MOST 108-2221-E-130-014
6 · The paper itself

Abstract

Many studies concern the generation of lossy mode resonances (LMRs) using metallic oxide thin films that are deposited on optical fiber. However, the LMR-based optical fiber sensors are frangible, do not allow easy surface modification, and are not suited to mass production. This study proposes an electrical field-induced LMR-based biosensor with an optical planar waveguide to replace surface modification and allow the mass production of protein biosensors and accelerate the speed of the analyte to decrease the detection time. Experimentally, the biosensor is evaluated using charged serum albumin molecules and characterized in terms of the LMR wavelength shift using an externally applied voltage for different durations. The externally applied voltage generates a significant electric field, which drives the non-neutralized biomolecules and increases the LMR wavelength shift. Our experimental results demonstrate that there are two different mechanisms of adsorption of serum albumin molecules for short-term and long-term observations. These are used to calculate the sensitivity of the biosensor. This electrical field-induced method is highly significant for the development and fabrication of LMR-based biosensors.

Indexed as

Biosensing TechniquesOptical DevicesElectricityEquipment DesignOptical FibersOxidesOxidesbiosensorbovine serum albuminelectrical-fieldlossy mode resonanceoptical planar waveguidesensitivity

Identifiers

PMID33803880
PMCPMC8003139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.