Evidence map›Paper›PMID 33803852›Full record

ReviewToxins2021

Shiga Toxins: An Update on Host Factors and Biomedical Applications.

Yang Liu, Songhai Tian, Hatim Thaker, Min Dong

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Redefining Shiga toxin-induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Shiga Toxin Induces ApoptosisJournal of microbiology and biotechnology · 2026
    Article
  4. Emerging hybrid shigatoxigenic and enteropathogenicClinical microbiology reviews · 2025
    Review
  5. Healthcare (Basel, Switzerland) · 2025
    Article
  6. Shiga toxin-producingFrontiers in microbiology · 2025
    Article
  7. Review
  8. Review
  9. AB Toxins as High-Affinity Ligands for Cell Targeting in Cancer Therapy.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Targeting the Inside of Cells with Biologicals: Toxin Routes in a Therapeutic Context.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  12. Review
  13. Review
  14. The "Big Six": Hidden Emerging Foodborne Bacterial Pathogens.Tropical medicine and infectious disease · 2022
    Review
  15. EnterohemorrhagicInternational journal of molecular sciences · 2022
    Review
  16. Article
  17. Article
  18. Diversity of Non-O157 Shiga Toxin-ProducingAnimals : an open access journal from MDPI · 2021
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Yang LiuDepartment of Nephrology, The First Hospital of Jilin University, Changchun 130021, China.ORCID 0000-0002-1775-9908
Songhai TianDepartment of Urology, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0001-6630-1904
Hatim ThakerDepartment of Urology, Boston Children's Hospital, Boston, MA 02115, USA.
Min DongDepartment of Urology, Boston Children's Hospital, Boston, MA 02115, USA.
Boston Children's Hospital · US

Funding

Research Training in Pediatric Urology/CHB T32T32DK060442 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI ADAM, ROSALYN M · 2002 to 2023
$2.5M
NIDDK NIH HHS T32 DK060442
6 · The paper itself

Abstract

Shiga toxins (Stxs) are classic bacterial toxins and major virulence factors of toxigenic

Indexed as

AnimalsCRISPR-Cas SystemsEscherichia coli InfectionsHemolytic-Uremic SyndromeHost-Pathogen InteractionsHumansImmunotoxinsModels, MolecularNeoplasmsProtein ConformationShiga-Toxigenic Escherichia coliShiga ToxinsStructure-Activity RelationshipTrihexosylceramidesglobotriaosylceramideImmunotoxinsShiga ToxinsTrihexosylceramidesbacterial toxinsEHECGb3hemolytic uremic syndromeimmunotoxinLAPTM4AShiga toxinShigellaTM9SF2toxins

Identifiers

PMID33803852
PMCPMC8003205
OpenAlexW3138389081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.