Evidence map›Paper›PMID 33803823›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis, Molecular Docking Studies and In Silico ADMET Screening of New Heterocycles Linked Thiazole Conjugates as Potent Anti-Hepatic Cancer Agents.

Huda R M Rashdan, Mohamed El-Naggar, Aboubakr H Abdelmonsef

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Design, synthetic approach,RSC advances · 2022
    Article
  4. Article
  5. Article
  6. Synthesis, characterization,RSC advances · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huda R M RashdanChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo 12622, Egypt.ORCID 0000-0001-7474-1678
Mohamed El-NaggarChemistry Department, Faculty of Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.
Aboubakr H AbdelmonsefChemistry Department, Faculty of Science, South Valley University, Qena 83523, Egypt.ORCID 0000-0002-4616-0224

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiazoles are important scaffolds in organic chemistry. Biosynthesis of thiazoles is considered to be an excellent target for the design of novel classes of therapeutic agents. In this study, a new series of 2-ethylidenehydrazono-5-arylazothiazoles

Indexed as

AnimalsAntineoplastic AgentsBALB 3T3 CellsBinding SitesComputer SimulationDrug Screening Assays, AntitumorHep G2 CellsHeterocyclic CompoundsHumansLiver NeoplasmsMiceMolecular Docking Simulationrho GTP-Binding ProteinsStructure-Activity RelationshipThiazolesAntineoplastic AgentsHeterocyclic Compoundsrho GTP-Binding ProteinsThiazoles1,2,3-triazolesanti-hepatic cancer agentsRho6 proteinthiazoles

Identifiers

PMID33803823
PMCPMC8003218

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.