Evidence map›Paper›PMID 33803717›Full record

ArticleInternational journal of molecular sciences2021

New Approach to Antifungal Activity of Fluconazole Incorporated into the Porous 6-Anhydro-α-l-Galacto-β-d-Galactan Structures Modified with Nanohydroxyapatite for Chronic-Wound Treatments-In Vitro Evaluation.

Justyna Rewak-Soroczynska, Paulina Sobierajska, Sara Targonska, Agata Piecuch, Lukasz Grosman, Jaroslaw Rachuna, Slawomir Wasik, Michal Arabski, Rafal Ogorek, Rafal J Wiglusz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Chitosan-based matrix as a carrier for bacteriophages.Applied microbiology and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Justyna Rewak-SoroczynskaInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0002-8139-144X
Paulina SobierajskaInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0001-5636-2826
Sara TargonskaInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0003-3133-0240
Agata PiecuchDepartment of Mycology and Genetics, University of Wroclaw, Przybyszewskiego 63, 51-148 Wroclaw, Poland.ORCID 0000-0001-7791-8379
Lukasz GrosmanInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.
Jaroslaw RachunaInstitute of Biology, Jan Kochanowski University, Uniwersytecka 7, 25-406 Kielce, Poland.
Slawomir WasikInstitute of Physics, Jan Kochanowski University, Swietokrzyska 15, 25-406 Kielce, Poland.ORCID 0000-0003-0107-4493
Michal ArabskiInstitute of Biology, Jan Kochanowski University, Uniwersytecka 7, 25-406 Kielce, Poland.ORCID 0000-0002-9712-9286
Rafal OgorekDepartment of Mycology and Genetics, University of Wroclaw, Przybyszewskiego 63, 51-148 Wroclaw, Poland.ORCID 0000-0003-0564-7797
Rafal J WigluszInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0001-8458-1532
Polish Academy of Sciences · PLJan Kochanowski University · PLUniversity of Wrocław · PL

Funding

Narodowym Centrum Nauki UMO-2015/19/B/ST5/01330Narodowym Centrum Nauki UMO-2016/21/B/NZ6/01157Narodowym Centrum Nauki UMO-2018/28/T/ST5/00326
6 · The paper itself

Abstract

New fluconazole-loaded, 6-Anhydro-α-l-Galacto-β-d-Galactan hydrogels incorporated with nanohydroxyapatite were prepared and their physicochemical features (XRD, X-ray Diffraction; SEM-EDS, Scanning Electron Microscopy-Energy Dispersive X-ray Spectroscopy; ATR-FTIR, Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy), fluconazole release profiles and enzymatic degradation were determined. Antifungal activity of pure fluconazole was tested using

Indexed as

Antifungal AgentsBiofilmsChronic DiseaseDurapatiteFluconazoleFungiGalactansHydrogelsKineticsMicrobial Sensitivity TestsMuramidaseNanoparticlesPlanktonPorositySpectroscopy, Fourier Transform InfraredTime FactorsAntifungal AgentsDurapatiteFluconazoleGalactansHydrogelsMuramidasechronic woundsdrug carriersfluconazolefungal infectionshydrogels

Identifiers

PMID33803717
PMCPMC8003069
OpenAlexW3137357977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.