Evidence map›Paper›PMID 33803503›Full record

ReviewInternational journal of molecular sciences2021

Liver Transplantation for Colorectal Liver Metastases: Current Management and Future Perspectives.

Serban Puia-Negulescu, Fanny Lebossé, Jean-Yves Mabrut, Xavier Muller, Guillaume Rossignol, Teresa Antonini, Domitille Erard, Sylvie Radenne, Marielle Guillet, Jean-Christophe Souquet and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Serban Puia-NegulescuDepartment of Digestive Surgery and Liver Transplantation, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Fanny LebosséDepartment of Hepatology, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Jean-Yves MabrutDepartment of Digestive Surgery and Liver Transplantation, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Xavier MullerDepartment of Digestive Surgery and Liver Transplantation, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.ORCID 0000-0002-8849-5495
Guillaume RossignolDepartment of Pediatric Surgery, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, University of Lyon I, 69500 Lyon, France.
Teresa AntoniniDepartment of Hepatology, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Domitille ErardDepartment of Hepatology, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Sylvie RadenneDepartment of Hepatology, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Marielle GuilletDepartment of Hepatogastroenterology, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Jean-Christophe SouquetDepartment of Hepatogastroenterology, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Kayvan MohkamDepartment of Digestive Surgery and Liver Transplantation, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.
Mickael LesurtelDepartment of Digestive Surgery and Liver Transplantation, Croix Rousse University Hospital, University of Lyon I, 69004 Lyon, France.ORCID 0000-0003-2397-4599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with nonresectable liver metastases from colorectal cancer have few therapeutic options and a dismal prognosis. Although liver transplantation for this indication has historically a poor reputation, recent advances in the field of chemotherapy and immunosuppression have paved the way to revisit the concept. New data have shown promising results that need to be validated in several ongoing clinical trials. Since liver grafts represent a scarce resource, several new tools are being explored to expand the donor pool for this indication. The purpose of this review is to present all current available data and perspectives about liver transplantation for nonresectable liver metastases from colorectal cancer.

Indexed as

Liver TransplantationClinical Trials as TopicColorectal NeoplasmsHumansLiver NeoplasmsNeoplasm Recurrence, LocalPrognosiscolorectal cancercolorectal liver metastasesliver transplantationorgan donationrecurrence

Identifiers

PMID33803503
PMCPMC8002956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.