Evidence map›Paper›PMID 33803502›Full record

ReviewInternational journal of molecular sciences2021

Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis.

Seyedeh Maryam Hosseinikhah, Mahmood Barani, Abbas Rahdar, Henning Madry, Rabia Arshad, Vahideh Mohammadzadeh, Magali Cucchiarini

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Inflammatory factors collaboratively linkFrontiers in immunology · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Receptors expressions on peripheral lymphocytes and CD4Immunity, inflammation and disease · 2023
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. The Advances and Biomedical Applications of Imageable Nanomaterials.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Seyedeh Maryam HosseinikhahNanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad 91886-17871, Iran.ORCID 0000-0001-9565-3730
Mahmood BaraniDepartment of Chemistry, Shahid Bahonar University of Kerman, Kerman 761691411, Iran.ORCID 0000-0002-1711-2522
Abbas RahdarDepartment of Physics, Faculty of Science, University of Zabol, Zabol 538-9861, Iran.ORCID 0000-0003-4766-9214
Henning MadryCenter of Experimental Orthopaedics, Saarland University Medical Center, D-66421 Homburg/Saar, Germany.ORCID 0000-0002-8612-4842
Rabia ArshadDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Vahideh MohammadzadehDepartment of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Science, Mashhad 91886-17871, Iran.
Magali CucchiariniCenter of Experimental Orthopaedics, Saarland University Medical Center, D-66421 Homburg/Saar, Germany.ORCID 0000-0003-0323-8922
Mashhad University of Medical Sciences · IRSaarland University · DEQuaid-i-Azam University · PKShahid Bahonar University of Kerman · IRZabol University · IR

Funding

Open Access Publishing programme Saarland University
6 · The paper itself

Abstract

Nanomaterials have received increasing attention due to their unique chemical and physical properties for the treatment of rheumatoid arthritis (RA), the most common complex multifactorial joint-associated autoimmune inflammatory disorder. RA is characterized by an inflammation of the synovium with increased production of proinflammatory cytokines (IL-1, IL-6, IL-8, and IL-10) and by the destruction of the articular cartilage and bone, and it is associated with the development of cardiovascular disorders such as heart attack and stroke. While a number of imaging tools allow for the monitoring and diagnosis of inflammatory arthritis, and despite ongoing work to enhance their sensitivity and precision, the proper assessment of RA remains difficult particularly in the early stages of the disease. Our goal here is to describe the benefits of applying various nanomaterials as next-generation RA imaging and detection tools using contrast agents and nanosensors and as improved drug delivery systems for the effective treatment of the disease.

Indexed as

Theranostic NanomedicineAnimalsAntirheumatic AgentsArthritis, RheumatoidHumansInflammationNanostructuresAntirheumatic Agentsinflammatory arthritisnanodiagnosisnanotreatments

Identifiers

PMID33803502
PMCPMC8002885
OpenAlexW3135943075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.