Evidence map›Paper›PMID 33803361›Full record

ArticleInternational journal of molecular sciences2021

Preclinical Evaluation of

Maryam Oroujeni, Sara S Rinne, Anzhelika Vorobyeva, Annika Loftenius, Joachim Feldwisch, Per Jonasson, Vladimir Chernov, Anna Orlova, Fredrik Y Frejd, Vladimir Tolmachev

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Detection of HER2 expression usingBreast cancer research : BCR · 2024
    Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Monte Carlo-derivedMedical physics · 2023
    Article
  8. Review
  9. Phase I clinical evaluation ofTheranostics · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maryam OroujeniDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0003-2660-9837
Sara S RinneDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0003-2141-3982
Anzhelika VorobyevaDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0002-4778-3909
Annika LofteniusAffibody AB, 171 65 Solna, Sweden.
Joachim FeldwischAffibody AB, 171 65 Solna, Sweden.
Per JonassonAffibody AB, 171 65 Solna, Sweden.
Vladimir ChernovResearch Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia.
Anna OrlovaDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0001-6120-2683
Fredrik Y FrejdDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0002-6122-1734
Uppsala University · SEAffibody (Sweden) · SERussian Academy of Sciences · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2019-1925
6 · The paper itself

Abstract

Radionuclide imaging of HER2 expression in tumours may enable stratification of patients with breast, ovarian, and gastroesophageal cancers for HER2-targeting therapies. A first-generation HER2-binding affibody molecule [

Indexed as

Antineoplastic Agents, ImmunologicalKidneyNeoplasms, ExperimentalRadiopharmaceuticalsTechnetiumTomography, Emission-Computed, Single-PhotonAnimalsCell Line, TumorErb-b2 Receptor Tyrosine KinasesFemaleHumansMiceMice, Inbred BALB CMice, NudeTissue DistributionXenograft Model Antitumor AssaysAntineoplastic Agents, ImmunologicalERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesRadiopharmaceuticalsTechnetiumaffibody moleculeHER2radionuclide molecular imagingsecond-generation scaffoldtechnetium-99m

Identifiers

PMID33803361
PMCPMC7967187
OpenAlexW3134334047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.