Evidence map›Paper›PMID 33803355›Full record

ArticleMolecules (Basel, Switzerland)2021

Design and Synthesis of Non-Covalent Imidazo[1,2-

Manvendra Kumar, Gaurav Joshi, Sahil Arora, Tashvinder Singh, Sajal Biswas, Nisha Sharma, Zahid Rafiq Bhat, Kulbhushan Tikoo, Sandeep Singh, Raj Kumar

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Design and Pictet-Spengler enabled synthesis of carboxamide-substituted imidazo[1,2-Journal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. Review
  3. Synthesis and Biological Activity of Azolo[Molecules (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Article
  6. Mechanisms and markers of lung ageing in health and disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Scope of tetrazolo[1,5-Beilstein journal of organic chemistry · 2022
    Article
  15. 29th Annual GP2A Medicinal Chemistry Conference.Pharmaceuticals (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Manvendra KumarLaboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151401, Punjab, India.
Gaurav JoshiLaboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151401, Punjab, India.
Sahil AroraLaboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151401, Punjab, India.ORCID 0000-0001-7911-5609
Tashvinder SinghDepartment of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda 151401, Punjab, India.
Sajal BiswasLaboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151401, Punjab, India.
Nisha SharmaDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar 160062, Punjab, India.ORCID 0000-0002-7593-2676
Zahid Rafiq BhatDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar 160062, Punjab, India.
Kulbhushan TikooDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar 160062, Punjab, India.
Sandeep SinghDepartment of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda 151401, Punjab, India.
Raj KumarLaboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151401, Punjab, India.ORCID 0000-0001-5113-6627
Central University of Punjab · INNational Institute of Pharmaceutical Education and Research (NIPER) - Ahmedabad · IN

Funding

Science and Engineering Research Board EMR/2017/002702
6 · The paper itself

Abstract

A series of 30 non-covalent imidazo[1,2-

Indexed as

A549 CellsAntineoplastic AgentsCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationDrug Resistance, NeoplasmDrug Screening Assays, AntitumorErbB ReceptorsErlotinib HydrochlorideGefitinibHumansImidazolesInhibitory Concentration 50Lung NeoplasmsMolecular Docking SimulationMutationAntineoplastic AgentsEGFR protein, humanErbB ReceptorsErlotinib HydrochlorideGefitinibImidazolesProtein Kinase InhibitorsQuinoxalinesanticancer agentsimidazo[1,2-a]quinoxalinemutant EGFR inhibitorsnon-covalent EGFR inhibitors

Identifiers

PMID33803355
PMCPMC7967119
OpenAlexW3135228596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.