Evidence map›Paper›PMID 33803352›Full record

ReviewInternational journal of environmental research and public health2021

Pandemics and Burden of Stroke and Epilepsy in Sub-Saharan Africa: Experience from a Longstanding Health Programme.

Massimo Leone, Fausto Ciccacci, Stefano Orlando, Sandro Petrolati, Giovanni Guidotti, Noorjehan Abdul Majid, Victor Tamba Tolno, JeanBaptiste Sagno, Darlington Thole, Fabio Massimo Corsi and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Epilepsy and access to care in africa, from failure to success, a personal experience.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Stroke in Sierra Leone. the stroke risk factors for people with HIV: A prospective case-control study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Massimo LeoneThe Foundation of the Carlo Besta IRCCS Neurologic Institute, 20133 Milan, Italy.ORCID 0000-0001-7475-4049
Fausto CiccacciUniCamillus Saint Camillus International, University of Health Sciences, 00100 Rome, Italy.ORCID 0000-0003-0262-707X
Stefano OrlandoUniversity of Rome Tor Vergata, 00100 Rome, Italy.ORCID 0000-0001-9706-4075
Sandro PetrolatiSan Camillo Hospital Department of Cardioscience, 00100 Rome, Italy.
Giovanni GuidottiAzienda Sanitaria Locale (ASL) Roma 1 Regione Lazio, 00100 Rome, Italy.
Noorjehan Abdul MajidCommunity of S. Egidio DREAM Program, Maputo 1102, Mozambique.
Victor Tamba TolnoCommunity of S. Egidio DREAM Program, Blantyre 312224, Malawi.
JeanBaptiste SagnoCommunity of S. Egidio DREAM Program, Blantyre 312224, Malawi.
Darlington TholeCommunity of S. Egidio DREAM Program, Balaka 302100, Malawi.
Fabio Massimo CorsiSalvator Mundi International Hospital Neurology, 00100 Rome, Italy.
Michelangelo BartoloTelemedicine Department San Giovanni Addolorata Hospital, 00100 Rome, Italy.ORCID 0000-0002-5148-0599
Maria Cristina MarazziLibera Università Maria SS. Assunta, 00100 Rome, Italy.
ASL Roma · ITAzienda Ospedaliera San Giovanni Addolorata · ITFondazione IRCCS Istituto Neurologico Carlo Besta · ITIRCCS San Camillo Hospital · ITLibera Università Maria SS. Assunta · ITSaint Camillus International University of Health and Medical Sciences · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eighty percent of people with stroke live in low- to middle-income nations, particularly in sub-Saharan Africa (SSA) where stroke has increased by more than 100% in the last decades. More than one-third of all epilepsy-related deaths occur in SSA. HIV infection is a risk factor for neurological disorders, including stroke and epilepsy. The vast majority of the 38 million people living with HIV/AIDS are in SSA, and the burden of neurological disorders in SSA parallels that of HIV/AIDS. Local healthcare systems are weak. Many standalone HIV health centres have become a platform with combined treatment for both HIV and noncommunicable diseases (NCDs), as advised by the United Nations. The COVID-19 pandemic is overwhelming the fragile health systems in SSA, and it is feared it will provoke an upsurge of excess deaths due to the disruption of care for chronic diseases such as HIV, TB, hypertension, diabetes, and cerebrovascular disorders. Disease Relief through Excellent and Advanced Means (DREAM) is a health programme active since 2002 to prevent and treat HIV/AIDS and related disorders in 10 SSA countries. DREAM is scaling up management of NCDs, including neurologic disorders such as stroke and epilepsy. We described challenges and solutions to address disruption and excess deaths from these diseases during the ongoing COVID-19 pandemic.

Indexed as

COVID-19EpilepsyHIV InfectionsStrokeAfrica South of the SaharaHumansPandemicsSARS-CoV-2care disruptionCOVID-19DREAM programmeepilepsyHIV/AIDSmedical educationpandemicretentionstrokesub-Saharan Africa

Identifiers

PMID33803352
PMCPMC7967260
OpenAlexW3135668646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.