Evidence map›Paper›PMID 33803325›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Antimicrobial Stewardship Program Implementation in a Saudi Medical City: An Exploratory Case Study.

Saleh Alghamdi, Ilhem Berrou, Eshtyag Bajnaid, Zoe Aslanpour, Abdul Haseeb, Mohamed Anwar Hammad, Nada Shebl

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saleh AlghamdiDepartment of Clinical Pharmacy, Faculty of Clinical Pharmacy, Albaha University, Albaha 65779-77388, Saudi Arabia.ORCID 0000-0002-7975-933X
Ilhem BerrouFaculty of Health & Applied Sciences, University of the West of England, Staple Hill, Bristol BS16 1DD, UK.ORCID 0000-0003-3811-4735
Eshtyag BajnaidDepartment of Clinical Pharmacy, Pharmaceutical Services Administration, King Abdullah Medical City, Makkah 11176, Saudi Arabia.
Zoe AslanpourDepartment of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.ORCID 0000-0002-2567-0540
Abdul HaseebDepartment of Clinical Pharmacy, College of Pharmacy, Umm Al Qura University, Makkah 77207, Saudi Arabia.ORCID 0000-0003-2455-5054
Mohamed Anwar HammadDepartment of Clinical Pharmacy, Faculty of Clinical Pharmacy, Albaha University, Albaha 65779-77388, Saudi Arabia.
Nada SheblDepartment of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial stewardship programs (ASPs) in hospitals have long been shown to improve antimicrobials' use and reduce the rates of antimicrobial resistance. However, their implementation in hospitals, especially in developing countries such as Saudi Arabia, remains low. One of the main barriers to implementation is the lack of knowledge of how to implement them. This study aims to explore how an antimicrobial stewardship programme was implemented in a Saudi hospital, the challenges faced and how they were overcome, and the program outcomes. A key stakeholder case study design was used, involving in-depth semi-structured interviews with the core members of the ASP team and analysis of 35 ASP hospital documents. ASP implementation followed a top-down approach and involved an initial preparatory phase and an implementation phase, requiring substantial infectious diseases and clinical pharmacy input throughout. Top management support was key to the successful implementation. ASP implementation reduced rates of multi-drug resistance and prescription of broad-spectrum antimicrobials. The implementation of ASPs in hospital is administrator rather than clinician driven. Outsourcing expertise and resources may help hospitals address the initial implementation challenges.

Indexed as

antimicrobial stewardship programshospitalsmulti-drug resistance

Identifiers

PMID33803325
PMCPMC8000012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.