Evidence map›Paper›PMID 33803287›Full record

ReviewBrain sciences2021

Neuroimaging Correlates of Cognitive Dysfunction in Adults with Multiple Sclerosis.

Maria Petracca, Giuseppe Pontillo, Marcello Moccia, Antonio Carotenuto, Sirio Cocozza, Roberta Lanzillo, Arturo Brunetti, Vincenzo Brescia Morra

Abstract readReview
In one paragraph

Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  13. Classification of multiple sclerosis patients based on structural disconnection: A robust feature selection approach.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria PetraccaDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Giuseppe PontilloDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0001-5425-1890
Marcello MocciaDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-2613-3090
Antonio CarotenutoDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-1574-9693
Sirio CocozzaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Roberta LanzilloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0001-6388-8180
Arturo BrunettiDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Vincenzo Brescia MorraDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment is a frequent and meaningful symptom in multiple sclerosis (MS), caused by the accrual of brain structural damage only partially counteracted by effective functional reorganization. As both these aspects can be successfully investigated through the application of advanced neuroimaging, here, we offer an up-to-date overview of the latest findings on structural, functional and metabolic correlates of cognitive impairment in adults with MS, focusing on the mechanisms sustaining damage accrual and on the identification of useful imaging markers of cognitive decline.

Indexed as

atrophycognitive dysfunctionmagnetic resonance imagingmultiple sclerosisneuroimagingpositron emission tomographysodium

Identifiers

PMID33803287
PMCPMC8000635

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.