Evidence map›Paper›PMID 33802937›Full record

ReviewInternational journal of molecular sciences2021

The Role of CTLA4 and Its Polymorphisms in Solid Organ and Haematopoietic Stem Cell Transplantation.

Jakub Rosik, Bartosz Szostak, Filip Machaj, Andrzej Pawlik

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jakub RosikPomeranian Medical University, Department of Physiology, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0001-7377-4566
Bartosz SzostakPomeranian Medical University, Department of Physiology, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
Filip MachajPomeranian Medical University, Department of Physiology, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
Andrzej PawlikPomeranian Medical University, Department of Physiology, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0001-6557-1208
Pomeranian Medical University · PL

Funding

Minister of Science and Higher Education 00/ RID/2018/19
6 · The paper itself

Abstract

HLA matching, transplantation technique, or underlying disease greatly influences the probability of long-term transplantation success. It has been hypothesised that genetic variation affecting antigen presentation also contributes to the outcomes of both solid organ transplantation and allogeneic haematopoietic stem cell transplantation (AHSCT). Those genes, along with those responsible for innate and adaptive immunity, have become targets of investigation. In this review, we focus on the role of CTLA4 in the process of acute graft rejection and summarise the progress in our understanding of its role in predicting the outcome. We present the results of the latest studies investigating the link between

Indexed as

Genetic Predisposition to DiseaseHematopoietic Stem Cell TransplantationPolymorphism, GeneticCTLA-4 AntigenHumansImmunomodulationTreatment OutcomeCTLA-4 AntigenAHSCTCTLA-4GVHDkidney transplantationliver transplantation

Identifiers

PMID33802937
PMCPMC8002677
OpenAlexW3136891327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.