Evidence map›Paper›PMID 33802884›Full record

ArticleMolecules (Basel, Switzerland)2021

Theasaponin E

Bo Li, Tuantuan Tong, Ning Ren, Gary O Rankin, Yon Rojanasakul, Youying Tu, Yi Charlie Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Bo LiDepartment of Tea Science, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-7294-6888
Tuantuan TongDepartment of Tea Science, Zhejiang University, Hangzhou 310058, China.
Ning RenDepartment of Tea Science, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-2104-6158
Gary O RankinDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25755, USA.ORCID 0000-0002-5385-3512
Yon RojanasakulDepartment of Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA.
Youying TuDepartment of Tea Science, Zhejiang University, Hangzhou 310058, China.
Yi Charlie ChenCollege of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA.ORCID 0000-0001-6865-9512
Alderson Broaddus University · USZhejiang University · CNMarshall University · USWest Virginia University · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
NIGMS NIH HHS U54 GM104942NIH HHS P20GM103434
6 · The paper itself

Abstract

Novel therapeutic strategies for ovarian cancer treatment are in critical need due to the chemoresistance and adverse side effects of platinum-based chemotherapy. Theasaponin E

Indexed as

Angiogenesis InhibitorsAnimalsAntineoplastic AgentsApoptosisAtaxia Telangiectasia Mutated ProteinsCamellia sinensisCell Line, TumorCell MovementCell SurvivalChorioallantoic MembraneCisplatinDrug Resistance, NeoplasmFemaleG2 Phase Cell Cycle CheckpointsGene Expression Regulation, NeoplasticHumansAngiogenesis InhibitorsAntineoplastic AgentsAtaxia Telangiectasia Mutated ProteinsATM protein, humanCisplatinMTOR protein, humanOleanolic AcidPlant ExtractsProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePTEN protein, humanSaponinstheasaponin E1TOR Serine-Threonine KinasesVascular Endothelial Growth Factor AVEGFA protein, humanangiogenesisapoptosisCamellia sinensis seedscell cycle arrestovarian cancertheasaponin E1

Identifiers

PMID33802884
PMCPMC8002815
OpenAlexW3135987424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.