Evidence map›Paper›PMID 33802882›Full record

ArticleInternational journal of molecular sciences2021

Polysaccharides-Based Complex Particles' Protective Role on the Stability and Bioactivity of Immobilized Curcumin.

Camelia-Elena Iurciuc Tincu, Leonard Ionuţ Atanase, Christine Jérôme, Vincent Sol, Patrick Martin, Marcel Popa, Lăcrămioara Ochiuz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Camelia-Elena Iurciuc TincuDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, 700115 Iaşi, Romania.
Leonard Ionuţ AtanaseDepartment of Biomaterials, Faculty of Dental Medicine, Apollonia University, 11 Pacurari Street, 700355 Iasi, Romania.ORCID 0000-0002-3657-1492
Christine JérômeCenter for Education and Research on Macromolecules, CESAM-RU, University of Liège, Allée du 6 août 13, 4000 Liège, Belgium.ORCID 0000-0001-8442-5740
Vincent SolLaboratoire PEIRENE EA 7500, University of Limoges, 87000 Limoges, France.ORCID 0000-0003-0175-0156
Patrick MartinUniLaSalle, Unité Transformations & Agroressources, Université d'Artois, ULR7519, 62408 Béthune, France.ORCID 0000-0001-7507-5910
Marcel PopaDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Protection of the Environment, Gheorghe Asachi Technical University, 73 Prof. Dr. Docent Dimitrie Mangeron Street, 700050 Iasi, Romania.ORCID 0000-0003-4929-0830
Lăcrămioara OchiuzDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, 700115 Iaşi, Romania.ORCID 0000-0001-6447-0958
Grigore T. Popa University of Medicine and Pharmacy · ROAcademia Oamenilor de Știință din România · ROApollonia University · ROUniversité d'Artois · FRUniversité de Limoges · FRUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The curcumin degradation represents a significant limitation for its applications. The stability of free curcumin (FC) and immobilized curcumin in complex particles (ComPs) based on different polysaccharides was studied under the action of several factors. Ultraviolet-visible (UV-VIS) and Fourier-transform infrared (FTIR) spectroscopy proved the FC photodegradation and its role as a metal chelator: 82% of FC and between 26% and 39.79% of curcumin within the ComPs degraded after exposure for 28 days to natural light. The degradation half-life (t

Indexed as

AdsorptionAnimalsAntioxidantsBiphenyl CompoundsBuffersCattleCurcuminFlavonoidsFree Radical ScavengersHydrogen-Ion ConcentrationInhibitory Concentration 50IonsMetalsPhenolsPicratesPolysaccharides1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsBuffersCurcuminFlavonoidsFree Radical ScavengersIonsMetalsPhenolsPicratesPolysaccharidesProtective AgentsSerum Albumin, BovineSolutionsantioxidant activityBSA adsorptioncurcumin metal complexesimmobilized curcuminpH and light stabilitypolymeric matrixpolysaccharides particles

Identifiers

PMID33802882
PMCPMC8002829
OpenAlexW3137877106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.