Evidence map›Paper›PMID 33802838›Full record

ArticleInternational journal of molecular sciences2021

Expression and Localization of Thrombospondins, Plastin 3, and STIM1 in Different Cartilage Compartments of the Osteoarthritic Varus Knee.

Daniela Mählich, Anne Glasmacher, Ilka Müller, Johannes Oppermann, David Grevenstein, Peer Eysel, Juliane Heilig, Brunhilde Wirth, Frank Zaucke, Anja Niehoff

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Daniela MählichInstitute of Biomechanics and Orthopaedics, German Sport University Cologne, 50933 Cologne, Germany.
Anne GlasmacherCologne Center of Musculoskeletal Biomechanics (CCMB), Medical Faculty, University of Cologne, 50931 Cologne, Germany.
Ilka MüllerInstitute of Human Genetics, Center for Molecular Medicine, Center for Rare Disorders, University of Cologne, Kerpener Str. 34, 50931 Cologne, Germany.
Johannes OppermannCologne Center of Musculoskeletal Biomechanics (CCMB), Medical Faculty, University of Cologne, 50931 Cologne, Germany.
David GrevensteinCologne Center of Musculoskeletal Biomechanics (CCMB), Medical Faculty, University of Cologne, 50931 Cologne, Germany.ORCID 0000-0003-4823-7739
Peer EyselCologne Center of Musculoskeletal Biomechanics (CCMB), Medical Faculty, University of Cologne, 50931 Cologne, Germany.
Juliane HeiligCologne Center of Musculoskeletal Biomechanics (CCMB), Medical Faculty, University of Cologne, 50931 Cologne, Germany.
Brunhilde WirthInstitute of Human Genetics, Center for Molecular Medicine, Center for Rare Disorders, University of Cologne, Kerpener Str. 34, 50931 Cologne, Germany.ORCID 0000-0003-4051-5191
Frank ZauckeDr. Rolf M. Schwiete Research Unit for Osteoarthritis, Department of Orthopaedics (Friedrichsheim), University Hospital Frankfurt, Goethe University, Marienburgstraße 2, 60528 Frankfurt, Germany.ORCID 0000-0002-7680-9354
Anja NiehoffInstitute of Biomechanics and Orthopaedics, German Sport University Cologne, 50933 Cologne, Germany.ORCID 0000-0002-4165-0929
University of Cologne · DEGerman Sport University Cologne · DEGoethe University Frankfurt · DE

Funding

Deutsche Forschungsgemeinschaft FOR2722 (project no. 407176282 and 407168728Köln Fortune Program, Medical Faculty, University of Cologne, Cologne, Germany 289/2019
6 · The paper itself

Abstract

Osteoarthritis (OA) is a multifactorial disease which is characterized by a change in the homeostasis of the extracellular matrix (ECM). The ECM is essential for the function of the articular cartilage and plays an important role in cartilage mechanotransduction. To provide a better understanding of the interaction between the ECM and the actin cytoskeleton, we investigated the localization and expression of the Ca

Indexed as

AgedAged, 80 and overCartilage, ArticularCartilage Oligomeric Matrix ProteinChondrocytesFemaleHumansKnee JointMaleMembrane GlycoproteinsMicrofilament ProteinsMiddle AgedOsteoarthritis, KneeProtein TransportStromal Interaction Molecule 1ThrombospondinsCartilage Oligomeric Matrix ProteinMembrane GlycoproteinsMicrofilament ProteinsplastinStromal Interaction Molecule 1Thrombospondinsarticular cartilageCOMPosteoarthritisplastin 3STIM1TSP-1

Identifiers

PMID33802838
PMCPMC8002632
OpenAlexW3137574103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.