Evidence map›Paper›PMID 33802823›Full record

ArticleVeterinary sciences2021

Phenotype of the Aging-Dependent Spontaneous Onset of Hearing Loss in DBA/2 Mice.

Min-Soo Seo, Byeonghyeon Lee, Kyung-Ku Kang, Soo-Eun Sung, Joo-Hee Choi, Si-Joon Lee, Young-In Kim, Young-Suk Jung, Un-Kyung Kim, Kil Soo Kim

Abstract read
In one paragraph

Article in Veterinary sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Dysregulation ofLearning & memory (Cold Spring Harbor, N.Y.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min-Soo SeoLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41016, Korea.
Byeonghyeon LeeDepartment of Biology, College of Natural Sciences, Kyungpook National University, Daegu 41016, Korea.
Kyung-Ku KangLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41016, Korea.
Soo-Eun SungLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41016, Korea.ORCID 0000-0001-9971-2443
Joo-Hee ChoiLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41016, Korea.
Si-Joon LeeLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41016, Korea.
Young-In KimKPC Corporation, Gwangju 12773, Korea.
Young-Suk JungCollege of Pharmacy, Pusan National University, Busan 46241, Korea.
Un-Kyung KimDepartment of Biology, College of Natural Sciences, Kyungpook National University, Daegu 41016, Korea.
Kil Soo KimLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41016, Korea.

Funding

Ministry of Food and Drug Safety National Laboratory Animal Resources (NLAR) from the Ministry of Food and Drug Safety in 2018
6 · The paper itself

Abstract

DBA/2 mice are a well-known animal model for hearing loss developed due to intrinsic properties of these animals. However, results on the phenotype of hearing loss in DBA/2 mice have been mainly reported at an early stage in mice aged ≤7 weeks. Instead, the present study evaluated the hearing ability at 5, 13, and 34 weeks of age using DBA/2korl mice. Auditory brainstem response test was performed at 8-32 KHz at 5, 13, and 34 weeks of age, and hearing loss was confirmed to be induced in a time-dependent manner. In addition, histopathological evaluation at the same age confirmed the morphological damage of the cochlea. The findings presented herein are the results of the long-term observation of the phenotype of hearing loss in DBA/2 mice and can be useful in studies related to aging-dependent hearing loss.

Indexed as

agingDBA/2 micehearing losslaboratory animals

Identifiers

PMID33802823
PMCPMC8002487

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.