Evidence map›Paper›PMID 33802791›Full record

ArticleCancers2021

A Drastic Shift in Lipid Adducts in Colon Cancer Detected by MALDI-IMS Exposes Alterations in Specific K

Jone Garate, Albert Maimó-Barceló, Joan Bestard-Escalas, Roberto Fernández, Karim Pérez-Romero, Marco A Martínez, Mª Antònia Payeras, Daniel H Lopez, José Andrés Fernández, Gwendolyn Barceló-Coblijn

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Ceramide Transfer Protein (CERT): An Overlooked Molecular Player in Cancer.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jone GarateDepartment of Physical Chemistry, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Albert Maimó-BarcelóInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.ORCID 0000-0003-0553-1743
Joan Bestard-EscalasInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.ORCID 0000-0003-4917-3781
Roberto FernándezDepartment of Physical Chemistry, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Karim Pérez-RomeroInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.
Marco A MartínezInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.ORCID 0000-0002-9859-0840
Mª Antònia PayerasInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.
Daniel H LopezInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.
José Andrés FernándezDepartment of Physical Chemistry, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Gwendolyn Barceló-CoblijnInstitut d'Investigació Sanitària Illes Balears (IdISBa, Health Research Institute of the Balearic Islands), 07120 Palma, Spain.ORCID 0000-0003-1017-5616
Health Research Institute of the Balearic Islands · ESUniversity of the Basque Country · ES

Funding

Basque Government IT1162-19European Regional Development Fund N/AEuropean Social Fund N/AGovernment of the Balearic Islands FPI/2160/2018, FPI/1787/2015, JQ-SP 18/17Instituto de Salud Carlos III CP12/03338, PI16/02200 and CPII17/00005
6 · The paper itself

Abstract

Even though colorectal cancer (CRC) is one of the most preventable cancers, it is one of the deadliest, and recent data show that the incidence in people <50 years has unexpectedly increased. While new techniques for CRC molecular classification are emerging, no molecular feature is as yet firmly associated with prognosis. Imaging mass spectrometry (IMS) lipidomic analyses have demonstrated the specificity of the lipid fingerprint in differentiating pathological from healthy tissues. During IMS lipidomic analysis, the formation of ionic adducts is common. Of particular interest is the [Na

Indexed as

colorectal cancerion adductslipidomicspotassium channels

Identifiers

PMID33802791
PMCPMC8061771
OpenAlexW3136798930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.