Evidence map›Paper›PMID 33802782›Full record

ArticleNutrients2021

Macronutrient Quality and All-Cause Mortality in the SUN Cohort.

Susana Santiago, Itziar Zazpe, Cesar I Fernandez-Lazaro, Víctor de la O, Maira Bes-Rastrollo, Miguel Ángel Martínez-González

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susana SantiagoDepartment of Nutrition and Food Sciences and Physiology, Campus Universitario, School of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-6820-2819
Itziar ZazpeDepartment of Nutrition and Food Sciences and Physiology, Campus Universitario, School of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-8787-2981
Cesar I Fernandez-LazaroDepartment of Preventive Medicine and Public Health, Campus Universitario, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-2366-2528
Víctor de la ODepartment of Preventive Medicine and Public Health, Campus Universitario, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9916-275X
Maira Bes-RastrolloDepartment of Preventive Medicine and Public Health, Campus Universitario, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9139-4206
Miguel Ángel Martínez-GonzálezDepartment of Preventive Medicine and Public Health, Campus Universitario, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3917-9808

Funding

Instituto de Salud Carlos III and European Regional Development Fund (FEDER) (RD 06/0045, CIBER-OBN, Grants PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795, PI20/00564 and G03/140),the Navarra Regional Government (45/2011, 122/2014, 41/2016), and the University of Navarra
6 · The paper itself

Abstract

No previous study has assessed the relationship between overall macronutrient quality and all-cause mortality. We aimed to prospectively examine the association between a multidimensional macronutrient quality index (MQI) and all-cause mortality in the SUN (Seguimiento Universidad de Navarra) (University of Navarra Follow-Up) study, a Mediterranean cohort of middle-aged adults. Dietary intake information was obtained from a validated 136-item semi-quantitative food-frequency questionnaire. We calculated the MQI (categorized in quartiles) based on three quality indexes: the carbohydrate quality index (CQI), the fat quality index (FQI), and the healthy plate protein source quality index (HPPQI). Among 19,083 participants (mean age 38.4, 59.9% female), 440 deaths from all causes were observed during a median follow-up of 12.2 years (IQR, 8.3-14.9). No significant association was found between the MQI and mortality risk with multivariable-adjusted hazard ratio (HR) for the highest vs. the lowest quartile of 0.79 (95% CI, 0.59-1.06; P

Indexed as

MortalityNutritional StatusAdultDiet, HealthyFemaleHumansMaleNutrientsProspective StudiesSpainNutrientsall-cause mortalitycarbohydratesfatmacronutrient qualityproteinsSUN cohort

Identifiers

PMID33802782
PMCPMC8002396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.