Evidence map›Paper›PMID 33802755›Full record

ArticleNutrients2021

Cloudy Apple Juice Fermented by

Mengzhen Han, Meina Zhang, Xiaowei Wang, Xue Bai, Tianli Yue, Zhenpeng Gao

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Apple Juice Fermented withFoods (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Anti-Obesity Effects ofFood science & nutrition · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mengzhen HanCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Meina ZhangCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Xiaowei WangCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Xue BaiCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Tianli YueCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Zhenpeng GaoCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Northwest A&F University · CN

Funding

key research and development plan of Shanxi Province,China 2020NY-096National Key R&D Program of China 2017YFD0400702
6 · The paper itself

Abstract

Obesity and hyperglycemia are two serious chronic diseases that are increasing in incidence worldwide. This research aimed to develop a fermented cloudy apple juice with good hyperglycemia intervention activities. Here, cloudy apple juice (CAJ), cloudy apple juice rich in polyphenols (CAJP) and fermented cloudy apple juice rich in polyphenols (FCAJP) were prepared sequentially, and then the effects of the three apple juices on weight, lipid level, gut microbiota composition and intestinal tract health were evaluated for obese mice induced by a high-fat diet. The research findings revealed that the FCAJP showed potential to inhibit the weight gain of mice, reduce fat accumulation, and regulate the blood lipid levels of obese mice by decreasing the ratio of the Firmicutes/Bacteroidotas, improving the Sobs, Ace, and Chao indexes of the gut microbiota and protecting intestinal tract health. In addition, the FCAJP augmented the abundance of Akkermansia and Bacteroides, which were positively related to SCFAs in cecal contents. This study inferred that FCAJP could be developed as a healthy food for preventing obesity and hyperglycemia.

Indexed as

LactobacillusMalusAnimalsCecumFatty AcidsFermentationFruit and Vegetable JuicesGastrointestinal MicrobiomeIntestinal MucosaLipidsLiverMaleMiceMice, Inbred C57BLObesityOxidative StressFatty AcidsLipidsRNA, Ribosomal, 16Sgut microbiotaintestinal tract healthLactobacilluspolyphenols

Identifiers

PMID33802755
PMCPMC8002442
OpenAlexW3138852253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.