Evidence map›Paper›PMID 33802736›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device.

Hiroyuki Yazu, Eisuke Shimizu, Shinri Sato, Naohiko Aketa, Taiichiro Katayama, Ryota Yokoiwa, Yasunori Sato, Kazumi Fukagawa, Yoko Ogawa, Kazuo Tsubota and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Development of the AI Pipeline for Corneal Opacity Detection.Bioengineering (Basel, Switzerland) · 2024
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  9. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hiroyuki YazuDepartment of Ophthalmology, Tsurumi University School of Dental Medicine, Kanagawa 230-0063, Japan.ORCID 0000-0002-7371-6558
Eisuke ShimizuDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.ORCID 0000-0002-3422-8578
Shinri SatoDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.
Naohiko AketaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.ORCID 0000-0002-0188-1255
Taiichiro KatayamaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.
Ryota YokoiwaOUI Inc., Tokyo 160-0022, Japan.
Yasunori SatoDepartment of Preventive Medicine and Public Health, Biostatistics at Clinical and Translational Research Center, Keio University School of Medicine, Tokyo 160-0016, Japan.
Kazumi FukagawaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.
Yoko OgawaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.
Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-0016, Japan.ORCID 0000-0002-8874-7111
Hiroshi FujishimaDepartment of Ophthalmology, Tsurumi University School of Dental Medicine, Kanagawa 230-0063, Japan.

Funding

Casio Science Promotion Foundation 38-40
6 · The paper itself

Abstract

backgroundThe incidence of allergic conjunctival diseases (ACDs) is gradually increasing worldwide. Both ophthalmologists and non-ophthalmologists prescribe eye drops to treat ACDs; however, there are many cases which are treated without sufficient examination and diagnosis of the eyes. We have invented a portable, recordable, and smartphone-attachable slit-lamp device-Smart Eye Camera (SEC). The purpose of this study was to compare the diagnostic abilities of ACDs between the SEC and the conventional, non-portable slit-lamp microscope.

methodsThis prospective observational study included 32 eyes of 17 Japanese patients (mean age: 21.5 ± 14.8 years; range: 11-51 years; female: 5). The severity of 10 objective signs in the palpebral conjunctiva, bulbar conjunctiva, limbus, and cornea were scored on a grading scale of 0 to 4 (0 = normal; 1+ = mild; 2+ = moderate; 3+ = severe), respectively. First, the conventional slit-lamp microscope was used to examine the grade of the ACDs. Second, another ophthalmologist filmed the eyes using the SEC and two other ophthalmologists evaluated the grades on another day. The correlation and inter-rater reproducibility in total scores among the two devices were determined.

resultsTotal scores of clinical signs, evaluated by the two approaches, correlated significantly (both eyes: r = 0.918 (95% CI: 0.839 to 0.959;

conclusionsThe SEC is as reliable as the conventional non-portable slit-lamp microscope for assessing ACDs.

Indexed as

allergic conjunctivital diseasesconventional slit-lamp microscopeportablerecordablesmart eye camera

Identifiers

PMID33802736
PMCPMC8002473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.