Evidence map›Paper›PMID 33802594›Full record

ArticleMolecules (Basel, Switzerland)2021

Biotransformation of Cortisone with

Federico Zappaterra, Stefania Costa, Daniela Summa, Valerio Bertolasi, Bruno Semeraro, Paola Pedrini, Raissa Buzzi, Silvia Vertuani

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Catabolic Mechanism of 17β-Estradiol inJournal of microbiology and biotechnology · 2026
    Article
  2. A Marine-Derived Steroid fromMarine drugs · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Federico ZappaterraDepartment of Life Sciences and Biotechnology, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0001-5852-2942
Stefania CostaDepartment of Life Sciences and Biotechnology, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-7555-2681
Daniela SummaDepartment of Life Sciences and Biotechnology, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-1483-268X
Valerio BertolasiDepartment of Chemical and Pharmaceutical Sciences, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Bruno SemeraroGATE SRL, Via L. Borsari 46, 44121 Ferrara, Italy.
Paola PedriniDepartment of Life Sciences and Biotechnology, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Raissa BuzziDepartment of Life Sciences and Biotechnology, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Silvia VertuaniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
University of Ferrara · IT

Funding

COSMAST (S.V. grant 2020)
6 · The paper itself

Abstract

Cortisone is a steroid widely used as an anti-inflammatory drug able to suppress the immune system, thus reducing inflammation and attendant pain and swelling at the site of an injury. Due to its numerous side effects, especially in prolonged and high-dose therapies, the development of the pharmaceutical industry is currently aimed at finding new compounds with similar activities but with minor or no side effects. Biotransformations are an important methodology towards more sustainable industrial processes, according to the principles of "green chemistry". In this work, the biotransformation of cortisone with

Indexed as

Anti-Inflammatory AgentsBiotransformationCortisoneGreen Chemistry TechnologyRhodococcusSteroidsAnti-Inflammatory AgentsCortisoneSteroidsbiotransformationcortisoneRhodococcus rhodniisteroids

Identifiers

PMID33802594
PMCPMC7962003
OpenAlexW3134495072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.