ArticleJournal of functional morphology and kinesiology2021
Effectiveness of Rehabilitative Intervention on Pain, Postural Balance, and Quality of Life in Women with Multiple Vertebral Fragility Fractures: A Prospective Cohort Study.
Article in Journal of functional morphology and kinesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06842758 (Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures
Who cites it
20 citing papers in PubMed, 21 citations in OpenAlex.
- Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial.Medicina (Kaunas, Lithuania) · 2023Trial
- Effects of physical therapy modalities for early postoperative pain following total knee arthroplasty: a systematic review and network meta-analysis.Frontiers in rehabilitation sciences · 2026Review
- The role of Power Doppler in ultrasound-guided percutaneous procedures: the Jet sign.European journal of translational myology · 2025Article
- Effective treatment of adolescent idiopathic scoliosis with the PosturalSpineEuropean journal of translational myology · 2025Article
- Feasibility and tolerability of electrical muscle stimulation during rehabilitation in older adults with osteoporotic vertebral fractures.Osteoporosis and sarcopenia · 2025Article
- Conservative Treatment with Teriparatide Versus Vertebroplasty for Acute Osteoporotic Vertebral Compression Fractures: A Meta-Analysis.Journal of clinical medicine · 2025Review
- New horizons for adolescent idiopathic scoliosis treatment through PosturalSpineEuropean journal of translational myology · 2025Article
- Padua Days on Muscle and Mobility Medicine, March 25-29, 2025, Hotel Petrarca, Euganean Thermae, Italy: Program and Abstracts.European journal of translational myology · 2025Article
- Pain characterization in osteosarcopenia: an exploratory study.Frontiers in rehabilitation sciences · 2025Article
- Active Breaks Reduce Back Overload during Prolonged Sitting: Ergonomic Analysis with Infrared Thermography.Journal of clinical medicine · 2024Article
- Therapeutic advantage of teriparatide in very elderly patients with proximal femoral fractures: a functional and BMD analysis.BMC musculoskeletal disorders · 2024Article
- Article
- Enhanced Stature in the Elderly: The Immediate Impact of Acute Postural Exercises.Sports (Basel, Switzerland) · 2024Article
- Effectiveness rehabilitative therapy and Pridinol Mesylate in low back pain.Frontiers in medicine · 2024Article
- Risk of primary osteoporosis score (RPOPs): an algorithm model for primary osteoporosis risk assessment in grass-roots hospital.BMC musculoskeletal disorders · 2022Article
- What are the efficacy and safety of pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic kidney disease stages 3-5D? - A Cochrane Review summary with commentary.Journal of musculoskeletal & neuronal interactions · 2022Review
- The Refraction Assessment and the Electronic Trial Frame Measurement during Standing or Sitting Position Can Affect Postural Stability.International journal of environmental research and public health · 2022Article
- What are the efficacy and safety of bisphosphonates and RANK-ligand-inhibitors for men with prostate cancer and bone metastases? - A Cochrane Review summary with commentary.Journal of musculoskeletal & neuronal interactions · 2021Article
- Assessment of Quality of Life and Pain Severity in Older Men with Osteoporosis: Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Prevalence and Characteristics of Spinal Sagittal Malalignment in Patients with Osteoporosis.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with vertebral fragility fractures often experience chronic pain, postural and balance disorders, and poor quality of life (QoL). Although several studies have investigated the role of rehabilitation in severe osteoporosis, the effectiveness of this intervention in patients with multiple vertebral fractures is poorly known. The aim of our longitudinal cohort study is to evaluate the effectiveness of rehabilitation, including postural training, resistance exercises, and visual stabilization exercises, for a 7-week period, on the pain, postural balance, and QoL of subjects with at least two vertebral fragility fractures receiving denosumab and vitamin D. We investigated, before (T0) and after (T1, at 7 weeks) rehabilitation, the following outcome measures on 28 patients: pain (Numerical Rating Scale (NRS)), self-perceived QoL (36-Item Short Form Survey (SF-36) and Mini-Osteoporosis Quality of Life Questionnaire (Mini-OQOL)), dizziness (Dizziness Handicap Inventory (DHI-I)), mobility (Timed-Up and Go (TUG) test), and instrumental posturographic assessment (FreeMed posturography system). At the end of the treatment, improvements of pain and QoL were recorded. Pain relief was highly obtained in patients with more than two vertebral fractures. Moreover, a significant functional improvement (TUG test) was found in those with two vertebral fractures, without any statistically significant change reported for other outcomes. Our findings suggest that combined intervention, including anti-osteoporotic drugs and postural rehabilitation, should be proposed to osteoporotic patients with multiple vertebral fractures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.