ArticleSensors (Basel, Switzerland)2021
Detection of Dental Caries and Cracks with Quantitative Light-Induced Fluorescence in Comparison to Radiographic and Visual Examination: A Retrospective Case Study.
Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07664046 (A Three-arm Randomized Controlled Trial Evaluating the Effectiveness of Self- Assembling Peptide P11-4 in the Remineralization of Enamel Carious White Spot Lesions), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Three-arm Randomized Controlled Trial Evaluating the Effectiveness of Self- Assembling Peptide P11-4 in the Remineralization of Enamel Carious White Spot Lesions
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Diagnostic accuracy of quantitative light-induced fluorescence in detecting caries of various types and locations: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Paired in vivo diagnostic accuracy and reliability of QrayCam Pro and QrayPen for occlusal and proximal caries in permanent posterior teeth.BMC oral health · 2026Article
- Validation of Quantitative Light-Induced Fluorescence Digital Analysis for Assessing Early Dental Caries Depth: A Micro-Computed Tomography-BasedDentistry journal · 2025Article
- Automated Classification of Dental Caries in Bitewing Radiographs Using Machine Learning and the ICCMS Framework.International journal of dentistry · 2025Article
- Investigation of validity and inter examiner agreement of quantitative light induced fluorescent images in diagnosing cracked teeth.Scientific reports · 2024Article
- The Potential Role of Ionic Liquid as a Multifunctional Dental Biomaterial.Biomedicines · 2023Review
- Quantitative Evaluation of Caries and Calculus with Ultrahigh-Resolution Optical Coherence Tomography.Bioengineering (Basel, Switzerland) · 2023Article
- Use of Digital Diagnostic Aids for Initial Caries Detection: A Review.Dentistry journal · 2023Review
- Review
- Development of a Visualisation Approach for Analysing Incipient and Clinically Unrecorded Enamel Fissure Caries Using Laser-Induced Contrast Imaging, MicroRaman Spectroscopy and Biomimetic Composites: A Pilot Study.Journal of imaging · 2022Article
- Evaluation of dental caries detection with quantitative light-induced fluorescence in comparison to different field of view devices.Scientific reports · 2022Article
- Optical coherence tomography evaluation of deep dentin crack removal techniques.JADA foundational science · 2022Article
- Microbiome of Saliva and Plaque in Children According to Age and Dental Caries Experience.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to present an optimal diagnostic protocol by comparing and analyzing a conventional examination and the quantitative light-induced fluorescence (QLF) technique. Selected were 297 teeth of 153 patients to take QLF images and bitewing radiographs. Occlusal dental caries, proximal dental caries and cracks were evaluated and scored using QLF, X-ray and/or visual criteria. The sensitivity, specificity, and area under the curve (AUC) of a receiver operating characteristic analysis were calculated. Two fluorescence parameters (|ΔFmax| and ΔRmax) were utilized to evaluate the fluorescence pattern according to the severity of lesions based on QLF or X-ray criteria. QLF showed higher scores for detecting occlusal dental caries and cracks than the conventional method. ΔRmax increased more clearly than ΔFmax did with occlusal dental caries. The |ΔFmax| values of occlusal dental caries, proximal dental caries and cracks showed good AUC levels (0.84, 0.81 and 0.83, respectively). The ΔRmax of occlusal dental caries showed the highest AUC (0.91) and the ΔRmax of proximal dental caries showed a fail level (0.59) compared to bitewing radiographs. The QLF image could visualize and estimate the degree of occlusal dental caries or cracks. Consequently, the QLF technique may be an adjunct tool to conventional methods for the detection of occlusal caries and peripheral cracks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.