Evidence map›Paper›PMID 33802204›Full record

ArticleMicromachines2021

Generation of Photopolymerized Microparticles Based on PEGDA Using Microfluidic Devices. Part 1. Initial Gelation Time and Mechanical Properties of the Material.

José M Acosta-Cuevas, José González-García, Mario García-Ramírez, Víctor H Pérez-Luna, Erick Omar Cisneros-López, Rubén González-Nuñez, Orfil González-Reynoso

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  5. Article
  6. Hydrogels: Properties and Applications in Biomedicine.Molecules (Basel, Switzerland) · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

José M Acosta-CuevasChemical Engineering Department, CUCEI, Universidad de Guadalajara, Blvd.M. García Barragán # 1451, Guadalajara C.P. 44430, Jalisco, Mexico.
José González-GarcíaChemical Engineering Department, CUCEI, Universidad de Guadalajara, Blvd.M. García Barragán # 1451, Guadalajara C.P. 44430, Jalisco, Mexico.
Mario García-RamírezElectronics Department, CUCEI, Universidad de Guadalajara, Blvd.M. García Barragán # 1451, Guadalajara C.P. 44430, Jalisco, Mexico.ORCID 0000-0003-1947-9595
Víctor H Pérez-LunaDepartment of Chemical and Biological Engineering, Illinois Institute of Technology, 10 West 33rd Street, Chicago, IL 60616, USA.
Erick Omar Cisneros-LópezChemical Engineering Department, CUCEI, Universidad de Guadalajara, Blvd.M. García Barragán # 1451, Guadalajara C.P. 44430, Jalisco, Mexico.ORCID 0000-0002-1586-8043
Rubén González-NuñezChemical Engineering Department, CUCEI, Universidad de Guadalajara, Blvd.M. García Barragán # 1451, Guadalajara C.P. 44430, Jalisco, Mexico.
Orfil González-ReynosoChemical Engineering Department, CUCEI, Universidad de Guadalajara, Blvd.M. García Barragán # 1451, Guadalajara C.P. 44430, Jalisco, Mexico.ORCID 0000-0002-7721-1127
Universidad de Guadalajara · MXIllinois Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photopolymerized microparticles are made of biocompatible hydrogels like Polyethylene Glycol Diacrylate (PEGDA) by using microfluidic devices are a good option for encapsulation, transport and retention of biological or toxic agents. Due to the different applications of these microparticles, it is important to investigate the formulation and the mechanical properties of the material of which they are made of. Therefore, in the present study, mechanical tests were carried out to determine the swelling, drying, soluble fraction, compression, cross-linking density (Mc) and mesh size (ξ) properties of different hydrogel formulations. Tests provided sufficient data to select the best formulation for the future generation of microparticles using microfluidic devices. The initial gelation times of the hydrogels formulations were estimated for their use in the photopolymerization process inside a microfluidic device. Obtained results showed a close relationship between the amount of PEGDA used in the hydrogel and its mechanical properties as well as its initial gelation time. Consequently, it is of considerable importance to know the mechanical properties of the hydrogels made in this research for their proper manipulation and application. On the other hand, the initial gelation time is crucial in photopolymerizable hydrogels and their use in continuous systems such as microfluidic devices.

Indexed as

initial gelation timemicrofluidic devicesPEGDA Hydrogelphotopolymerization

Identifiers

PMID33802204
PMCPMC8001310
OpenAlexW3135790984

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.