Evidence map›Paper›PMID 33802142›Full record

ArticleMolecules (Basel, Switzerland)2021

Profiling of In Vitro Bioaccessibility and Intestinal Uptake of Flavonoids after Consumption of Commonly Available Green Tea Types.

Jeong-Ho Oh, Chan-Yang Lee, Yeong-Eun Lee, So-Hee Yoo, Jin-Oh Chung, Chan-Su Rha, Mi-Young Park, Yong-Deog Hong, Soon-Mi Shim

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jeong-Ho OhDepartment of Food Science and Biotechnology, Sejong University, 98 Gunja-dong, Seoul 143-747, Korea.
Chan-Yang LeeDepartment of Food Science and Biotechnology, Sejong University, 98 Gunja-dong, Seoul 143-747, Korea.ORCID 0000-0002-7332-8408
Yeong-Eun LeeDepartment of Food Science and Biotechnology, Sejong University, 98 Gunja-dong, Seoul 143-747, Korea.ORCID 0000-0001-6924-807X
So-Hee YooDepartment of Food Science and Biotechnology, Sejong University, 98 Gunja-dong, Seoul 143-747, Korea.ORCID 0000-0001-8090-4138
Jin-Oh ChungAMOREPACIFIC R&D Center, 1920, Yonggu-daero, Giheung-gu, Yongin-si 17074, Gyeonggi-do, Korea.ORCID 0000-0003-3077-1554
Chan-Su RhaAMOREPACIFIC R&D Center, 1920, Yonggu-daero, Giheung-gu, Yongin-si 17074, Gyeonggi-do, Korea.ORCID 0000-0003-4791-1314
Mi-Young ParkAMOREPACIFIC R&D Center, 1920, Yonggu-daero, Giheung-gu, Yongin-si 17074, Gyeonggi-do, Korea.
Yong-Deog HongAMOREPACIFIC R&D Center, 1920, Yonggu-daero, Giheung-gu, Yongin-si 17074, Gyeonggi-do, Korea.
Soon-Mi ShimDepartment of Food Science and Biotechnology, Sejong University, 98 Gunja-dong, Seoul 143-747, Korea.ORCID 0000-0002-5978-9662
Sejong University · KRAmorepacific (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to profile the bioaccessibility and intestinal absorption of epicatechins and flavonols in different forms of green tea and its formulation: loose leaf tea, powdered tea, 35% catechins containing GTE, and GTE formulated with green tea-derived polysaccharide and flavonols (CATEPLUS™). The bioaccessibillity and intestinal absorption of epicatechins and flavonols was investigated by using an in vitro digestion model system with Caco-2 cells. The bioaccessibility of total epicatechins in loose leaf tea, powdered tea, GTE, and CATEPLUS™ was 1.27%, 2.30%, 22.05%, and 18.72%, respectively, showing that GTE and CATEPLUS™ had significantly higher bioaccessibility than powdered tea and loose leaf tea. None of the flavonols were detected in powdered tea and loose leaf tea, but the bioaccessibility of the total flavonols in GTE and CATEPLUS™ was 85.74% and 66.98%, respectively. The highest intestinal absorption of epicatechins was found in CATEPLUS™ (171.39 ± 5.39 ng/mg protein) followed by GTE (57.38 ± 9.31), powdered tea (3.60 ± 0.67), and loose leaf tea (2.94 ± 1.03). The results from the study suggest that formulating green tea extracts rich in catechins with second components obtained from green tea processing could enhance the bioavailability of epicatechins.

Indexed as

AntioxidantsBiological AvailabilityBiological TransportCaco-2 CellsCatechinDigestionFlavonoidsFlavonolsHumansIntestinesModels, BiologicalPlant ExtractsTeaAntioxidantsCatechinFlavonoidsFlavonolsPlant ExtractsTeabioaccessibilityCATEPLUS™epicatechinsflavonolsGTEintestinal uptakeloose leaf teapowdered tea

Identifiers

PMID33802142
PMCPMC7999519
OpenAlexW3135303798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.