Evidence map›Paper›PMID 33802089›Full record

ArticleChildren (Basel, Switzerland)2021

Outcomes in Establishing Individual Vessel Patency for Pediatric Pulmonary Vein Stenosis.

Ryan Callahan, Kimberlee Gauvreau, Audrey C Marshall, Laureen M Sena, Christopher W Baird, Christina M Ireland, Kerry McEnaney, Elsa C Bjornlund, Juliana T Mendonca, Kathy J Jenkins

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00891527 phase1 / phase2completednot on this map

Adjunct Targeted Biologic Inhibition in Children With Multivessel Intraluminal Pulmonary Vein Stenosis

TypeinterventionalSponsorBoston Children's HospitalRan2008 to 2015Enrolled50ConditionsPulmonary Veno Occlusive DiseaseArmsBevacizumab (Avastin) and Imatinib Mesylate (Gleevec)
NCT06440408 phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Calculating Wall Shear Stress in Pulmonary Veins of Infants Using Cardiac Magnetic Resonance Imaging: A Pilot Study

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2024 to 2028Enrolled20ConditionsPulmonary Vein StenosisArmsFerumoxytol
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Management of Pediatric Pulmonary Vein Stenosis.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ryan CallahanDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-0030-7013
Kimberlee GauvreauDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Audrey C MarshallDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Laureen M SenaDepartment of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Christopher W BairdDepartment of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Christina M IrelandDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-3805-2191
Kerry McEnaneyDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Elsa C BjornlundDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Juliana T MendoncaDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Kathy J JenkinsDepartment of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-8702-988X
Boston Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to determine what patient and pulmonary vein characteristics at the diagnosis of intraluminal pulmonary vein stenosis (PVS) are predictive of individual vein outcomes. A retrospective, single-center, cohort sub-analysis of individual pulmonary veins of patients enrolled in the clinical trial NCT00891527 using imatinib mesylate +/- bevacizumab as adjunct therapy for the treatment of multi-vessel pediatric PVS between March 2009 and December 2014 was performed. The 72-week outcomes of the individual veins are reported. Among the 48 enrolled patients, 46 patients and 182 pulmonary veins were included in the study. Multivariable analysis demonstrated that patients with veins without distal disease at baseline (odds ratio, OR 3.69, 95% confidence interval, CI [1.52, 8.94],

Indexed as

congenital heart diseasedrug therapyoutcometreatment

Identifiers

PMID33802089
PMCPMC8000090
OpenAlexW3138957508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.