Evidence map›Paper›PMID 33802075›Full record

ArticleInternational journal of molecular sciences2021

A New Family of Benzo[

Alaa S Abd-El-Aziz, Azhaar Alsaggaf, Eman Assirey, Arshi Naqvi, Rawda M Okasha, Tarek H Afifi, Mohamed Hagar

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. A dendritic nanocatalyst (FeScientific reports · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Near-infrared voltage-sensitive dyes based on chromene donor.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alaa S Abd-El-AzizDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.
Azhaar AlsaggafDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.
Eman AssireyDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.ORCID 0000-0002-7312-4800
Arshi NaqviDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.ORCID 0000-0002-9211-7139
Rawda M OkashaDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.ORCID 0000-0001-9453-8132
Tarek H AfifiDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.ORCID 0000-0002-8029-4840
Mohamed HagarDepartment of Chemistry, College of Sciences, Taibah University, Yanbu 30799, Saudi Arabia.ORCID 0000-0003-0169-7738

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high biological activity of the chromene compounds coupled with the intriguing optical features of azo chromophores prompted our desire to construct novel derivatives of chromene incorporating azo moieties 4a-l, which have been prepared via a three-component reaction of 1-naphthalenol-4-[(4-ethoxyphenyl) azo], 1, with the benzaldehyde derivatives and malononitrile. The structural identities of the azo-chromene 4a-l were confirmed on the basis of their spectral data and elemental analysis, and a UV-visible study was performed in a Dimethylformamide (DMF) solution for these molecules. Additionally, the antimicrobial activity was investigated against four human pathogens (Gram-positive and Gram-negative bacteria) and four fungi, employing an agar well diffusion method, with their minimum inhibitory concentrations being reported. Molecules 4a, 4g, and 4h were discovered to be more efficacious against

Indexed as

Anti-Infective AgentsAntineoplastic AgentsAzo CompoundsBenzopyransComputer SimulationCell ProliferationEscherichia coliHCT116 CellsHep G2 CellsHumansMCF-7 CellsMucoralesNeoplasmsAnti-Infective AgentsAntineoplastic AgentsAzo CompoundsBenzopyransazo chromene dyesbiological assessmentDFT calculationsmolecular dockingSAR

Identifiers

PMID33802075
PMCPMC7998172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.