Evidence map›Paper›PMID 33802064›Full record

ArticleMolecules (Basel, Switzerland)2021

Caffeic and Dihydrocaffeic Acids Promote Longevity and Increase Stress Resistance in

Sofia M Gutierrez-Zetina, Susana González-Manzano, Begoña Ayuda-Durán, Celestino Santos-Buelga, Ana M González-Paramás

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Preclinical Catecholaminergic Biomarkers of Central Lewy Body Diseases.Journal of clinical neurology (Seoul, Korea) · 2026
    Review
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  9. The endophytic fungusFrontiers in pharmacology · 2022
    Article
  10. Current research in food science · 2022
    Review
  11. Multiple catechols in human plasma after drinking caffeinated or decaffeinated coffee.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2021
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sofia M Gutierrez-ZetinaGrupo de Investigación en Polifenoles (GIP-USAL), Unidad de Nutrición y Bromatología, Facultad de Farmacia, Campus Miguel de Unamuno, Universidad de Salamanca, 37007 Salamanca, Spain.
Susana González-ManzanoGrupo de Investigación en Polifenoles (GIP-USAL), Unidad de Nutrición y Bromatología, Facultad de Farmacia, Campus Miguel de Unamuno, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-5739-515X
Begoña Ayuda-DuránGrupo de Investigación en Polifenoles (GIP-USAL), Unidad de Nutrición y Bromatología, Facultad de Farmacia, Campus Miguel de Unamuno, Universidad de Salamanca, 37007 Salamanca, Spain.
Celestino Santos-BuelgaGrupo de Investigación en Polifenoles (GIP-USAL), Unidad de Nutrición y Bromatología, Facultad de Farmacia, Campus Miguel de Unamuno, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-6592-5299
Ana M González-ParamásGrupo de Investigación en Polifenoles (GIP-USAL), Unidad de Nutrición y Bromatología, Facultad de Farmacia, Campus Miguel de Unamuno, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-5477-0703

Funding

Consejería de Educación, Junta de Castilla y León CLU-2018-04 and SA093P20Ministerio de Ciencia e Innovación PID2019-106167RB-I00Ministerio de Economía y Competitividad AGL2015-64522-C2-2R
6 · The paper itself

Abstract

Caffeic and dihydrocaffeic acid are relevant microbial catabolites, being described as products from the degradation of different phenolic compounds i.e., hydroxycinnamoyl derivatives, anthocyanins or flavonols. Furthermore, caffeic acid is found both in free and esterified forms in many fruits and in high concentrations in coffee. These phenolic acids may be responsible for a part of the bioactivity associated with the intake of phenolic compounds. With the aim of progressing in the knowledge of the health effects and mechanisms of action of dietary phenolics, the model nematode

Indexed as

AnimalsAntioxidantsCaenorhabditis elegansCaenorhabditis elegans ProteinsCaffeic AcidsGene ExpressionLongevityOxidative StressSignal TransductionStress, PhysiologicalTranscription Factors3,4-dihydroxyphenylpropionic acidAntioxidantsCaenorhabditis elegans Proteinscaffeic acidCaffeic AcidsTranscription FactorsCaenorhabditis eleganscaffeic aciddihydrocaffeic acidIIS pathwaylifespanoxidative stressthermoresistance

Identifiers

PMID33802064
PMCPMC8001149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.