Evidence map›Paper›PMID 33802046›Full record

ReviewInternational journal of molecular sciences2021

Neuromyelitis Optica Spectrum Disorder Treatment-Current and Future Prospects.

Marta Waliszewska-Prosół, Justyna Chojdak-Łukasiewicz, Sławomir Budrewicz, Anna Pokryszko-Dragan

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  9. Overview of emerging therapies for demyelinating diseases.World journal of clinical cases · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marta Waliszewska-ProsółDepartment of Neurology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-9074-2803
Justyna Chojdak-ŁukasiewiczDepartment of Neurology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-0777-4565
Sławomir BudrewiczDepartment of Neurology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Anna Pokryszko-DraganDepartment of Neurology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica (NMO) is an immune-mediated demyelinative disorder of the central nervous system affecting mainly the optical nerves and the spinal cord. The recurrent course of the disease, with exacerbations and incomplete remissions, causes accumulating disability, which has a profound impact upon patients' quality of life. The discovery of antibodies against aquaporin 4 (AQP4) and their leading role in NMO etiology and the formulation of diagnostic criteria have improved appropriate recognition of the disease. In recent years, there has been rapid progress in understanding the background of NMO, leading to an increasing range of treatment options. On the basis of a review of the relevant literature, the authors present currently available therapeutic strategies for NMO as well as ongoing research in this field, with reference to key points of immune-mediated processes involved in the background of the disease.

Indexed as

Aquaporin 4AutoantibodiesHumansImmunoglobulin GMyelin-Oligodendrocyte GlycoproteinNeuromyelitis OpticaOptic NerveQuality of LifeRecurrenceSpinal CordAquaporin 4AutoantibodiesImmunoglobulin GMyelin-Oligodendrocyte Glycoproteinaquaporin 4autoimmune humoral responsedemyelinating diseasesneuromyelitis optica spectrum disordertreatment

Identifiers

PMID33802046
PMCPMC7998461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.