Evidence map›Paper›PMID 33801939›Full record

ReviewAntibiotics (Basel, Switzerland)2021

Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing.

Sandor Kasas, Anton Malovichko, Maria Ines Villalba, María Elena Vela, Osvaldo Yantorno, Ronnie G Willaert

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Real-time evaluation of macozinone activity againstAntimicrobial agents and chemotherapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandor KasasLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Anton MalovichkoLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Maria Ines VillalbaLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
María Elena VelaInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, and CONICET, Diagonal 113 y 64, 1900 La Plata, Argentina.
Osvaldo YantornoCentro de Investigación y Desarrollo en Fermentaciones Industriales (CINDEFI-CONICET-CCT La Plata), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, 1900 La Plata, Argentina.
Ronnie G WillaertInternational Joint Research Group VUB-EPFL NanoBiotechnology and NanoMedicine (NANO), Vrije Universiteit Brussel, 1050 Brussels, Belgium.ORCID 0000-0002-5400-7019

Funding

Agency for Promotion of Science and Technology of Argentina PICT 2016-0679Agency for Promotion of Science and Technology of Argentina PICT 2017-2444European Space Agency PRODEX Yeast NanomotionFonds Wetenschappelijk Onderzoek AUGE/13/19, I002620N, G068121NGebert Rüf Stiftung GRS-024/14NASA NNH16ZDA001N-CLDTCHPUE (CONICET) 22920170100100COSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 200021-144321, 407240-167137, CRSII5_173863, 310030L_197946
6 · The paper itself

Abstract

Rapid antibiotic susceptibility testing (AST) could play a major role in fighting multidrug-resistant bacteria. Recently, it was discovered that all living organisms oscillate in the range of nanometers and that these oscillations, referred to as nanomotion, stop as soon the organism dies. This finding led to the development of rapid AST techniques based on the monitoring of these oscillations upon exposure to antibiotics. In this review, we explain the working principle of this novel technique, compare the method with current ASTs, explore its application and give some advice about its implementation. As an illustrative example, we present the application of the technique to the slowly growing and pathogenic

Indexed as

atomic force microscopy (AFM)B. pertussisnanomotionrapid antibiotic susceptibility testing (AST)

Identifiers

PMID33801939
PMCPMC7999052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.