Evidence map›Paper›PMID 33801913›Full record

ArticleCancers2021

ECG Scoring for the Evaluation of Therapy-Naïve Cancer Patients to Predict Cardiotoxicity.

Julia Pohl, Raluca-Ileana Mincu, Simone M Mrotzek, Reza Wakili, Amir A Mahabadi, Sophia K Potthoff, Jens T Siveke, Ulrich Keller, Ulf Landmesser, Tienush Rassaf and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Julia PohlWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.ORCID 0000-0001-9142-4869
Raluca-Ileana MincuWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.
Simone M MrotzekWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.
Reza WakiliWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.
Amir A MahabadiWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.ORCID 0000-0003-2336-7991
Sophia K PotthoffDepartment of Cardiology, Charité University Medicine Berlin (CBF), 12203 Berlin, Germany.
Jens T SivekeWest German Cancer Center, Institute for Developmental Cancer Therapeutics, University Medicine Essen, 45147 Essen, Germany.ORCID 0000-0002-8772-4778
Ulrich KellerDepartment of Hematology, Oncology, and Tumor Immunology, Campus Benjamin Franklin, Charité University Medicine Berlin, 12203 Berlin, Germany.ORCID 0000-0002-8485-1958
Ulf LandmesserDepartment of Cardiology, Charité University Medicine Berlin (CBF), 12203 Berlin, Germany.
Tienush RassafWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.ORCID 0000-0001-8001-0265
Markus S AnkerDepartment of Cardiology, Charité University Medicine Berlin (CBF), 12203 Berlin, Germany.
Matthias TotzeckWest German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Medical Faculty, 45147 Essen, Germany.
West German Heart and Vascular Center Essen · DEGerman Centre for Cardiovascular Research · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate a new electrocardiographic (ECG) score reflecting domains of electrical and structural alterations in therapy-naïve cancer patients to assess their risk of cardiotoxicity.

methodsWe performed a retrospective analysis of 134 therapy-naïve consecutive cancer patients in our two university hospitals concerning four ECG score parameters: Contiguous Q-waves, markers of left ventricular (LV) hypertrophy, QRS duration and JTc prolongation. Cardiotoxicity was assessed after a short-term follow-up (up to 12 months).

resultsOf all the patients (

conclusionECG scoring prior to the start of anti-cancer therapies may help to identify therapy-naïve cancer patients at a higher risk for the development of cardiotoxicity.

Indexed as

cancercardio-oncologycardiotoxicityECGscore

Identifiers

PMID33801913
PMCPMC7999575
OpenAlexW3135833821

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.