Evidence map›Paper›PMID 33801847›Full record

ArticleMolecules (Basel, Switzerland)2021

Baicalin Represses Type Three Secretion System of

Pansong Zhang, Qiao Guo, Zhihua Wei, Qin Yang, Zisheng Guo, Lixin Shen, Kangmin Duan, Lin Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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  11. Frontiers in microbiology · 2024
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  12. Infection and immunity · 2023
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Pansong ZhangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an 710069, China.
Qiao GuoCollege of Natural Resources and Environment, Northwest A&F University, Yangling 712100, China.
Zhihua WeiKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an 710069, China.
Qin YangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an 710069, China.
Zisheng GuoKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an 710069, China.
Lixin ShenKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an 710069, China.
Kangmin DuanDepartment of Oral Biology & Medical Microbiology & Infectious Diseases, Rady Faculty of Health Sciences, University of Manitoba, 780 Bannatyne Ave., Winnipeg, MB R3E 0W2, Canada.ORCID 0000-0002-3016-786X
Lin ChenKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an 710069, China.ORCID 0000-0003-2322-4595
Ministry of Education of the People's Republic of China · CNNorthwest A&F University · CNUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutics that target the virulence of pathogens rather than their viability offer a promising alternative for treating infectious diseases and circumventing antibiotic resistance. In this study, we searched for anti-virulence compounds against

Indexed as

AnimalsAnti-Bacterial AgentsBacterial ProteinsBiofilmsChinaDrosophila melanogasterDrosophila ProteinsFemaleFlavonoidsModels, AnimalPseudomonas aeruginosaPseudomonas InfectionsQuinolonesQuorum SensingRatsRats, Sprague-Dawley2-heptyl-3-hydroxy-4-quinoloneAnti-Bacterial AgentsBacterial ProteinsbaicalinDrosophila ProteinsFlavonoidsQuinolonesTranscription FactorsType III Secretion SystemsVirulence Factorsbaicalinmouse lung infection modelPQS inhibitionPseudomonas aeruginosaType III secretion systemvirulence factors

Identifiers

PMID33801847
PMCPMC8001617
OpenAlexW3133633379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.