ReviewJournal of clinical medicine2021
Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant's: A Systematic Review.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Elimination of Enterococcus faecalis from root canal system using laser-activated nanoparticles: a systematic review.Lasers in medical science · 2023Pooled it
- Antibiofilm Substantivity of AgNPs in Clinical Oral Biofilms from Patients with Motor and Intellectual Disabilities: An In Vitro and Exploratory Study.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Article
- Green-SynthesizedJournal of functional biomaterials · 2026Article
- Applications of Nanomaterials in Restorative Dentistry and Endodontics: A Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Development of a nano antibiotic paste for lesion sterilization and tissue repair technique in pediatric dentistry.Scientific reports · 2025Article
- Synergistic antibiofilm activity of methylene blue and silver nanoparticle-mediated photothermal therapy against Enterococcus faecalis biofilm.Scientific reports · 2025Article
- Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles - AnJournal of pharmacy & bioallied sciences · 2025Article
- Anti-microbial effect of probiotic versus silver nanoparticle irrigant.Bioinformation · 2025Article
- Nanoparticles revolution: The role of gold and chitosan in endodontics irrigation.Bioinformation · 2025Article
- Unlocking the Potential of Silver Nanoparticles: From Synthesis to Versatile Bio-Applications.Pharmaceutics · 2024Review
- The Push-Out Bond Strength, Surface Roughness, and Antimicrobial Properties of Endodontic Bioceramic Sealers Supplemented with Silver Nanoparticles.Molecules (Basel, Switzerland) · 2024Article
- Application of Nanomaterials in Endodontics.BME frontiers · 2024Review
- Implementation of Silver Nanoparticles Green Synthesized with Leaf Extract ofCurrent pharmaceutical biotechnology · 2024Article
- The effect of nanobased irrigants on the root canal dentin microhardness: an ex-vivo study.BMC oral health · 2023Article
- Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review.Pharmaceutics · 2023Review
- Silver Nanoparticles Alone or in Combination with Calcium Hydroxide Modulate the Viability, Attachment, Migration, and Osteogenic Differentiation of Human Mesenchymal Stem Cells.International journal of molecular sciences · 2022Article
- Noncytotoxic silver nanoparticles as a new antimicrobial strategy.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Removal of microbes is imperative during endodontic therapy. Due to their antimicrobial property, silver nanoparticles have been used for endodontic irrigation of the root canals. The objective of the present study was to provide a qualitative analysis of the published literature assessing silver nanoparticles as root canal irrigants. A search of PubMed, SCOPUS, Web of Science, and Embase databases was done without any time restriction. Articles published in English were included. Data were extracted and the risk of bias was assessed. Of the 154 studies identified, after screening according to the inclusion criteria, five in vitro studies were included. The results indicate that silver nanoparticles have an anti-microbial effect to varying degrees depending on certain factors. Within the limitations of the present studies that have a moderate to low risk of bias, an antimicrobial effect of silver nanoparticles is observed. Silver nanoparticles have the potential to be used as endodontic irrigants, although their efficacy depends on particle size and the duration of contact which require further investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.