Evidence map›Paper›PMID 33801783›Full record

ArticleInternational journal of molecular sciences2021

Interleukin-13 Propagates Prothrombin Kringle-2-Induced Neurotoxicity in Hippocampi In Vivo via Oxidative Stress.

Jae Yeong Jeong, Rayul Wi, Young Cheul Chung, Byung Kwan Jin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jae Yeong JeongDepartment of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Rayul WiDepartment of Neuroscience, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Young Cheul ChungDepartment of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.
Byung Kwan JinDepartment of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Kyung Hee University · KRKorea Institute of Toxicology · KR

Funding

National Research Foundation of Korea NRF-2016R1A2B4010692National Research Foundation of Korea NRF-2017M3C7A1031105National Research Foundation of Korea NRF-2018R1A6A1A03025124National Research Foundation of Korea NRF-2019R1A2C2007897
6 · The paper itself

Abstract

The present study investigated expression of endogenous interleukin-13 (IL-13) and its possible function in the hippocampus of prothrombin kringle-2 (pKr-2)-lesioned rats. Here we report that intrahippocampal injection of pKr-2 revealed a significant loss of NeuN-immunopositive (NeuN

Indexed as

Oxidative StressAnimalsAstrocytesDNA DamageFemaleHippocampusInterleukin-13KringlesMacrophagesMicrogliaNeuronsNeutrophilsOxygenProtein DomainsProthrombinRatsInterleukin-13OxygenProthrombininterleukin-13 (IL-13)microglia/macrophages and neutrophilsoxidative/nitrosative stressprothrombin kringle-2 (pKr-2)reactive oxygen species (ROS)

Identifiers

PMID33801783
PMCPMC8036367
OpenAlexW3142424946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.