Evidence map›Paper›PMID 33801738›Full record

ArticleToxins2021

Systematic Evaluation of Parameters Important for Production of Native Toxin A and Toxin B from

Aria Aminzadeh, René Jørgensen

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aria AminzadehDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, 2300 Copenhagen, Denmark.ORCID 0000-0003-0819-7891
René JørgensenDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, 2300 Copenhagen, Denmark.ORCID 0000-0003-0672-466X
Statens Serum Institut · DK

Funding

Novo Nordisk Fonden NNF17OC0029548
6 · The paper itself

Abstract

In the attempt to improve the purification yield of native toxin A (TcdA) and toxin B (TcdB) from

Indexed as

Bacteriological TechniquesBacterial ProteinsBacterial ToxinsBuffersChromatography, Ion ExchangeClostridioides difficileCulture MediaEnterotoxinsHydrogen-Ion ConcentrationProtein StabilityBacterial ProteinsBacterial ToxinsBuffersCulture MediaEnterotoxinstcdA protein, Clostridium difficiletoxB protein, Clostridium difficileClostridioides difficileClostridium difficileculture mediaprotein purificationsandwich ELISATcdATcdBToxin AToxin Btoxin expression

Identifiers

PMID33801738
PMCPMC8066640
OpenAlexW3140498635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.