Evidence map›Paper›PMID 33801585›Full record

ReviewInternational journal of molecular sciences2021

Emerging Molecular Connections between NM23 Proteins, Telomeres and Telomere-Associated Factors: Implications in Cancer Metastasis and Ageing.

Shalu Sharma, Antara Sengupta, Shantanu Chowdhury

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Effects ofOpen life sciences · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shalu SharmaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Mathura Road, New Delhi 110025, India.
Antara SenguptaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Mathura Road, New Delhi 110025, India.
Shantanu ChowdhuryIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Mathura Road, New Delhi 110025, India.
Institute of Genomics and Integrative Biology · IN

Funding

DBT-Wellcome Trust India Alliance IA/S/18/2/504021
6 · The paper itself

Abstract

The metastasis suppressor function of NM23 proteins is widely understood. Multiple enzymatic activities of NM23 proteins have also been identified. However, relatively less known interesting aspects are being revealed from recent developments that corroborate the telomeric interactions of NM23 proteins. Telomeres are known to regulate essential physiological events such as metastasis, ageing, and cellular differentiation via inter-connected signalling pathways. Here, we review the literature on the association of NM23 proteins with telomeres or telomere-related factors, and discuss the potential implications of emerging telomeric functions of NM23 proteins. Further understanding of these aspects might be instrumental in better understanding the metastasis suppressor functions of NM23 proteins.

Indexed as

AgingGene Expression Regulation, NeoplasticNeoplasm MetastasisAnimalsCell DifferentiationCell MovementCell ProliferationCytoskeletonDNAG-QuadruplexesHumansLymphocyte ActivationMitochondriaNeoplasmsNM23 Nucleoside Diphosphate KinasesNucleoside Diphosphate Kinase DDNAMYC protein, humanNM23 Nucleoside Diphosphate KinasesNME1 protein, humanNME4 protein, humanNucleoside Diphosphate Kinase DProto-Oncogene Proteins c-mycTranscription FactorsageingcytoskeletonDNA bindingG-quadruplexmitochondriaNDPK proteinsprotein kinasetelomeretelomere length

Identifiers

PMID33801585
PMCPMC8036570
OpenAlexW3152200351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.