Evidence map›Paper›PMID 33801433›Full record

ArticleJournal of cardiovascular development and disease2021

Myocardial TGFβ2 Is Required for Atrioventricular Cushion Remodeling and Myocardial Development.

Aniket Bhattacharya, Nadia Al-Sammarraie, Mengistu G Gebere, John Johnson, John F Eberth, Mohamad Azhar

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. BMPR2 affects valve development via ECM-receptor interaction in zebrafish.Frontiers in cell and developmental biology · 2026
    Article
  4. Article
  5. Article
  6. A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aniket BhattacharyaDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.ORCID 0000-0002-6479-3981
Nadia Al-SammarraieDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
Mengistu G GebereDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.ORCID 0000-0002-1513-9844
John JohnsonDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
John F EberthDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.ORCID 0000-0003-1053-9045
Mohamad AzharDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.ORCID 0000-0001-9228-8096
University of South Carolina · US

Funding

NIH HHS R01HL126705, R01HL145064, R01HL145064-01S1School of Medicine, University of South Carolina Bob Price - Instrumentation Resource Facility Endowment Fund
6 · The paper itself

Abstract

Among the three transforming growth factor beta (TGFβ) ligands, TGFβ2 is essential for heart development and is produced by multiple cell types, including myocardium. Heterozygous mutations in

Indexed as

atrioventricular cushionAVSDmitral valvemyocardiumSMAD2TGFβ2

Identifiers

PMID33801433
PMCPMC7999251
OpenAlexW3134398645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.