Evidence map›Paper›PMID 33801311›Full record

ArticleJournal of clinical medicine2021

Prognostic Role of TAPSE to PASP Ratio in Patients Undergoing MitraClip Procedure.

Blanca Trejo-Velasco, Rodrigo Estevez-Loureiro, Fernando Carrasco-Chinchilla, Felipe Fernández-Vázquez, Dabit Arzamendi, Manuel Pan, Isaac Pascual, Luis Nombela-Franco, Ignacio J Amat-Santos, Xavier Freixa and 25 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impact of Right Ventricular to Pulmonary Artery Coupling on Survival Following Indirect Mitral Annuloplasty.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  10. Article
  11. Right ventricular to pulmonary arterial coupling as a predictor of survival in patients undergoing mitral valve surgery for mitral regurgitation.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. It's All About That Right Ventricle.Journal of the American Heart Association · 2024
    Article
  17. Article
  18. Review
  19. The tricuspid annular plane systolic excursion/PASP ratio's accuracy and validity in assessing the right ventricular function: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 20 institutions in 1 country.

Blanca Trejo-VelascoCardiology Department, University Hospital of Salamanca, Biomedical Research Institute of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0001-8163-5064
Rodrigo Estevez-LoureiroCardiology Department, Alvaro Cunqueiro University Hospital, 36213 Vigo, Spain.
Fernando Carrasco-ChinchillaCardiology Department, Virgen de la Victoria University Hospital, Biomedical Research Institute of Málaga, 29010 Málaga, Spain.
Felipe Fernández-VázquezCardiology Department, University Hospital of Leon, 24071 Leon, Spain.ORCID 0000-0001-7187-1290
Dabit ArzamendiCardiology Department, University Hospital Santa Creu i Sant Pau, 08041 Barcelona, Spain.
Manuel PanCardiology Department, University Hospital Reina Sofia, University of Cordoba and Maimonides Institute for Biomedical Research (IMIBIC), 14004 Córdoba, Spain.
Isaac PascualHeart Area, Asturias Central University Hospital, University of Oviedo, Health Research Institute, 33011 Oviedo, Spain.ORCID 0000-0001-5433-1364
Luis Nombela-FrancoCardiovascular Institute, Hospital Clínico San Carlos, Health Research Institute San Carlos (IdISSC), 28040 Madrid, Spain.ORCID 0000-0003-3438-8907
Ignacio J Amat-SantosBiomedical Research Networking Center on Cardiovascular Diseases (CIBERCV), 28029 Madrid, Spain.
Xavier FreixaCardiology Department, Clínic University Hospital of Barcelona, University of Barcelona, Biomedical Research Institute August Pi i Sunyer (IDIBAPS), 08041 Barcelona, Spain.
Rosa Ana Hernández-AntolínCardiology Department, Ramon y Cajal University Hospital, 28034 Madrid, Spain.
Ramiro Trillo-NoucheBiomedical Research Networking Center on Cardiovascular Diseases (CIBERCV), 28029 Madrid, Spain.
Leire Andraka IkazuriagaCardiology Department, University Hospital of Basurto, 48013 Bilbao, Spain.ORCID 0000-0001-9979-2498
José R López-MínguezCardiology Department, University Hospital of Badajoz, 06080 Badajoz, Spain.
Dario Sanmiguel CerveraCardiology Department, General University Hospital of Valencia, 46014 Valencia, Spain.
Juan SanchisBiomedical Research Networking Center on Cardiovascular Diseases (CIBERCV), 28029 Madrid, Spain.ORCID 0000-0003-0797-8709
José Luis Diez-GilCardiology Department, University & Polytechnical Hospital La Fe, 46026 Valencia, Spain.ORCID 0000-0001-9921-8023
Valeriano Ruiz-QuevedoCardiology Department, University Hospital of Navarra, 31008 Pamplona, Spain.
Cristóbal Urbano-CarrilloCardiology Department, Regional University Hospital of Málaga, 29010 Málaga, Spain.
Víctor Manuel Becerra-MuñozCardiology Department, Virgen de la Victoria University Hospital, Biomedical Research Institute of Málaga, 29010 Málaga, Spain.
Tomás Benito-GonzálezCardiology Department, University Hospital of Leon, 24071 Leon, Spain.ORCID 0000-0002-8428-9248
Chi Hion LiCardiology Department, University Hospital Santa Creu i Sant Pau, 08041 Barcelona, Spain.
Dolores MesaCardiology Department, University Hospital Reina Sofia, University of Cordoba and Maimonides Institute for Biomedical Research (IMIBIC), 14004 Córdoba, Spain.
Pablo AvanzasHeart Area, Asturias Central University Hospital, University of Oviedo, Health Research Institute, 33011 Oviedo, Spain.ORCID 0000-0002-4958-6108
Germán ArmijoCardiovascular Institute, Hospital Clínico San Carlos, Health Research Institute San Carlos (IdISSC), 28040 Madrid, Spain.ORCID 0000-0002-1521-412X
Ana María Serrador-FrutosCardiology Department, Clinic University Hospital of Valladolid, Heart Sciences Institute, 47003 Valladolid, Spain.
Laura SanchisCardiology Department, Clínic University Hospital of Barcelona, University of Barcelona, Biomedical Research Institute August Pi i Sunyer (IDIBAPS), 08041 Barcelona, Spain.ORCID 0000-0003-2516-8953
Covadonga Fernández-Golfín LobánCardiology Department, Ramon y Cajal University Hospital, 28034 Madrid, Spain.
Belén Cid-ÁlvarezBiomedical Research Networking Center on Cardiovascular Diseases (CIBERCV), 28029 Madrid, Spain.
José María Hernández-GarcíaCardiology Department, Virgen de la Victoria University Hospital, Biomedical Research Institute of Málaga, 29010 Málaga, Spain.
Carmen Garrote-ColomaCardiology Department, University Hospital of Leon, 24071 Leon, Spain.
Estefanía Fernández-PeregrinaCardiology Department, University Hospital Santa Creu i Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0002-3025-8251
Miguel RomeroCardiology Department, University Hospital Reina Sofia, University of Cordoba and Maimonides Institute for Biomedical Research (IMIBIC), 14004 Córdoba, Spain.
Víctor León ArgueroHeart Area, Asturias Central University Hospital, University of Oviedo, Health Research Institute, 33011 Oviedo, Spain.
Ignacio Cruz-GonzálezCardiology Department, University Hospital of Salamanca, Biomedical Research Institute of Salamanca (IBSAL), 37007 Salamanca, Spain.
Centro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital de León · ESHospital de Sant Pau · ESInstituto Maimónides de Investigación Biomédica de Córdoba · ESUniversidad de Oviedo · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESHospital Clínico San Carlos · ESInstituto Cajal · ESUniversidade de Santiago de Compostela · ESCentro de Implantología Cirugía Oral y Maxilofacial · ESHospital Clínico Universitario de Valladolid · ESHospital de Basurto · ESHospital General Universitario De Valencia · ESHospital Regional Universitario de Málaga · ESHospital Universitari i Politècnic La Fe · ESInstituto de Investigación Biomédica de Salamanca · ESUniversidad de Navarra · ESUniversidad de Salamanca · ESUniversitat de València · ESUniversity Hospital Complex Of Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter mitral valve repair (TMVR) is an effective therapy for high-risk patients with severe mitral regurgitation (MR) but heart failure (HF) readmissions and death remain substantial on mid-term follow-up. Recently, right ventricular (RV) to pulmonary arterial (PA) coupling has emerged as a relevant prognostic predictor in HF. In this study, we aimed to assess the prognostic value of tricuspid annular plane systolic excursion (TAPSE) to PA systolic pressure (PASP) ratio as a non-invasive measure of RV-to-PA coupling in patients undergoing TMVR with MitraClip (Abbott, CA, USA).

methodsMulticentre registry including 228 consecutive patients that underwent successful TMVR with MitraClip. The sample was divided in two groups according to TAPSE/PASP median value: 0.35. The primary combined endpoint encompassed HF readmissions and all-cause mortality.

resultsMean age was 72.5 ± 11.5 years and 154 (67.5%) patients were male. HF readmissions and all-cause mortality were more frequent in patients with TAPSE/PASP ≤ 0.35: Log-Rank 8.844,

conclusionsTAPSE/PASP ratio appears as a novel prognostic predictor in patients undergoing MitraClip implantation that might improve risk stratification and candidate selection.

Indexed as

MitraClipmitral valve regurgitationmitral valve repairpulmonary hypertensionright ventricular to pulmonary arterial couplingtransthoracic echocardiography

Identifiers

PMID33801311
PMCPMC7958333
OpenAlexW3134179118

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.