Evidence map›Paper›PMID 33801254›Full record

ArticleInternational journal of molecular sciences2021

ANT1 Activation and Inhibition Patterns Support the Fatty Acid Cycling Mechanism for Proton Transport.

Jürgen Kreiter, Anne Rupprecht, Sanja Škulj, Zlatko Brkljača, Kristina Žuna, Denis G Knyazev, Sarah Bardakji, Mario Vazdar, Elena E Pohl

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Interactions of Arachidonic Acid with AAC1 and UCP1.International journal of molecular sciences · 2025
    Article
  9. Mild Mitochondrial Uncoupling for True Ectopic Lipid Disposal.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Review
  12. Interconnected roles of mitochondrial carrier proteins ANT, PFrontiers in molecular biosciences · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Jürgen KreiterInstitute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria.ORCID 0000-0001-5877-762X
Anne RupprechtInstitute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria.
Sanja ŠkuljDivision of Organic Chemistry and Biochemistry, Rudjer Bošković Institute,10000 Zagreb, Croatia.ORCID 0000-0002-5471-3618
Zlatko BrkljačaDivision of Organic Chemistry and Biochemistry, Rudjer Bošković Institute,10000 Zagreb, Croatia.
Kristina ŽunaInstitute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria.
Denis G KnyazevInstitute of Biophysics, Johannes Kepler University, 4020 Linz, Austria.ORCID 0000-0003-3197-1849
Sarah BardakjiInstitute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria.
Mario VazdarDivision of Organic Chemistry and Biochemistry, Rudjer Bošković Institute,10000 Zagreb, Croatia.ORCID 0000-0001-6905-6174
Elena E PohlInstitute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria.ORCID 0000-0002-0604-5950
University of Veterinary Medicine Vienna · ATRuđer Bošković Institute · HRJohannes Kepler University of Linz · AT

Funding

Austrian Science Fund P31559Austrian Science Fund FWF P 31559Croatian Science Foundation IP-2019-04-3804
6 · The paper itself

Abstract

Adenine nucleotide translocase (ANT) is a well-known mitochondrial exchanger of ATP against ADP. In contrast, few studies have shown that ANT also mediates proton transport across the inner mitochondrial membrane. The results of these studies are controversial and lead to different hypotheses about molecular transport mechanisms. We hypothesized that the H

Indexed as

ProtonsAdenine Nucleotide Translocator 1AnimalsFatty AcidsIon TransportMembrane Potential, MitochondrialMiceMitochondriaProtein ConformationAdenine Nucleotide Translocator 1Fatty AcidsProtonsADP/ATP carrier proteinarachidonic acidfatty acid anion transportlong-chain fatty acidsmitochondrial transporterproton transport

Identifiers

PMID33801254
PMCPMC7958136
OpenAlexW3135154734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.