Evidence map›Paper›PMID 33800961›Full record

ReviewNutrients2021

In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?

Lauren R Brink, Maciej Chichlowski, Nitida Pastor, Athmaram Thimmasandra Narayanappa, Neil Shah

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lauren R BrinkMedical and Scientific Affairs, Nutrition, Reckitt Benckiser, Evansville, IN 47721, USA.ORCID 0000-0003-0191-5168
Maciej ChichlowskiMedical and Scientific Affairs, Nutrition, Reckitt Benckiser, Evansville, IN 47721, USA.ORCID 0000-0002-6004-2195
Nitida PastorMedical and Scientific Affairs, Nutrition, Reckitt Benckiser, Evansville, IN 47721, USA.
Athmaram Thimmasandra NarayanappaMicrobiome Management Science Platform, Reckitt Benckiser, Montvale, NJ 07645, USA.
Neil ShahMedical and Scientific Affairs, Nutrition, Reckitt Benckiser, Slough SL1 3UH, UK.
Reckitt Benckiser (United States) · USReckitt Benckiser (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2020, with the advent of a pandemic touching all aspects of global life, there is a renewed interest in nutrition solutions to support the immune system. Infants are vulnerable to infection and breastfeeding has been demonstrated to provide protection. As such, human milk is a great model for sources of functional nutrition ingredients, which may play direct roles in protection against viral diseases. This review aims to summarize the literature around human milk (lactoferrin, milk fat globule membrane, osteopontin, glycerol monolaurate and human milk oligosaccharides) and infant nutrition (polyunsaturated fatty acids, probiotics and postbiotics) inspired ingredients for support against viral infections and the immune system more broadly. We believe that the application of these ingredients can span across all life stages and thus apply to both pediatric and adult nutrition. We highlight the opportunities for further research in this field to help provide tangible nutrition solutions to support one's immune system and fight against infections.

Indexed as

AdultCOVID-19FemaleFood IngredientsFunctional FoodHumansImmune SystemInfantInfant Nutritional Physiological PhenomenaMaleMilk, HumanNutrition TherapySARS-CoV-2Food Ingredientsanti-viralglycerol monolauratehuman milk oligosaccharidesinfant nutritionlactoferrinmilk fat globule membraneosteopontinpolyunsaturated fatty acidspostbioticsprobiotics

Identifiers

PMID33800961
PMCPMC7999376
OpenAlexW3135488389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.