Evidence map›Paper›PMID 33800945›Full record

ArticleInternational journal of molecular sciences2021

Sperm Methylome Profiling Can Discern Fertility Levels in the Porcine Biomedical Model.

Fabio Pértille, Manuel Alvarez-Rodriguez, Arthur Nery da Silva, Isabel Barranco, Jordi Roca, Carlos Guerrero-Bosagna, Heriberto Rodriguez-Martinez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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  12. How Epigenetics Can Enhance Pig Welfare?Animals : an open access journal from MDPI · 2021
    Review
  13. Review
  14. Article
  15. Seminal Plasma: Relevant for Fertility?International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Fabio PértilleDepartment of Physics, Chemistry and Biology, Linköping University, SE-58183 Linköping, Sweden.ORCID 0000-0002-7214-9184
Manuel Alvarez-RodriguezDepartment of Biomedical & Clinical Sciences (BKV), Linköping University, SE-58185 Linköping, Sweden.ORCID 0000-0003-0120-354X
Arthur Nery da SilvaDepartment of Physics, Chemistry and Biology, Linköping University, SE-58183 Linköping, Sweden.ORCID 0000-0002-4668-9769
Isabel BarrancoDepartment of Biomedical & Clinical Sciences (BKV), Linköping University, SE-58185 Linköping, Sweden.ORCID 0000-0001-9873-814X
Jordi RocaDepartment of Medicine and Animal Surgery, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-4213-3093
Carlos Guerrero-BosagnaDepartment of Physics, Chemistry and Biology, Linköping University, SE-58183 Linköping, Sweden.
Heriberto Rodriguez-MartinezDepartment of Biomedical & Clinical Sciences (BKV), Linköping University, SE-58185 Linköping, Sweden.ORCID 0000-0002-5194-2124
Linköping University · SEUniversidad de Murcia · ES

Funding

FAPESP FAPESP projects #2016/20440-3 and #2018/13600-0.MINECO (Spain) and FEDER funds (EU) (AGL2015-69738-R AGL2015-69738-RResearch Council FORMAS, Stockholm Projects 2017-00946, 2018-01074 and 2019-00288Seneca Foundation Murcia, Spain (19892/GERM-15). 19892/GERM-15
6 · The paper itself

Abstract

A combined Genotyping By Sequencing (GBS) and methylated DNA immunoprecipitation (MeDIP) protocol was used to identify-in parallel-genetic variation (Genomic-Wide Association Studies (GWAS) and epigenetic differences of Differentially Methylated Regions (DMR) in the genome of spermatozoa from the porcine animal model. Breeding boars with good semen quality (

Indexed as

DNA MethylationAnimalsBase SequenceChromosomesFertilityGene LibraryGene OntologyGenome-Wide Association StudyHumansInfertility, MaleInsemination, ArtificialMaleModels, AnimalPolymorphism, Single NucleotideSeasonsSemen Analysisartificial inseminationfertilitygenotyping by sequencing (GBS)methylated DNA immunoprecipitation (MeDIP)pigprolificacyspermatozoa

Identifiers

PMID33800945
PMCPMC7961483
OpenAlexW3135462839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.