Evidence map›Paper›PMID 33800918›Full record

ArticleBiomolecules2021

Effects of Hypoxic Preconditioning and Vascular Endothelial Growth Factor on the Survival of Isolated Primary Retinal Ganglion Cells.

Hyoung Won Bae, Wungrak Choi, Ah Reum Hwang, Sang Yeop Lee, Gong Je Seong, Chan Yun Kim

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hyoung Won BaeInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Korea.
Wungrak ChoiInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Korea.
Ah Reum HwangInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Korea.
Sang Yeop LeeInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Korea.
Gong Je SeongInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Korea.
Chan Yun KimInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-8373-9999
Yonsei University · KR

Funding

faculty research grant of Yonsei University College of Medicine 6-2019-0140National Research Foundation of Korea (NRF) NRF-2019R1A2C1091089National Research Foundation of Korea (NRF) NRF-2019R1F1A1061795
6 · The paper itself

Abstract

This study aimed to investigate the effect of hypoxic preconditioning (HPC) on primary retinal ganglion cell (RGC) survival and the associated mechanism, including the role of vascular endothelial growth factor (VEGF). Retinas were separated from the enucleated eyeballs of Sprague-Dawley rats on postnatal days 1-4. RGCs were harvested using an immunopanning-magnetic separation system and maintained for 24 h in a defined medium. Hypoxic damage (0.3% O

Indexed as

AnimalsBlotting, WesternBrain-Derived Neurotrophic FactorEnzyme-Linked Immunosorbent AssayFlow CytometryIn Vitro TechniquesRatsRats, Sprague-DawleyRetinal Ganglion CellsVascular Endothelial Growth Factor ABrain-Derived Neurotrophic FactorVascular Endothelial Growth Factor Ahypoxic preconditioningretinal ganglion cellvascular endothelial growth factor

Identifiers

PMID33800918
PMCPMC8002095
OpenAlexW3134962547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.