Evidence map›Paper›PMID 33800736›Full record

ReviewCells2021

The Importance of

Melissa Vos, Christine Klein

Abstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Alterations in energy production in aFrontiers in aging neuroscience · 2026
    Article
  3. Endoplasmic Reticulum Proteins Impact Penetrance in aInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Mass spectrometry-based proteomics for biomarker discovery in theNeuroprotection (Chichester, England) · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Mitochondrial Complex I deficiency: guilty in Parkinson's disease.Signal transduction and targeted therapy · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Neurodegenerative Disorders: Spotlight on Sphingolipids.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Melissa VosInstitute of Neurogenetics, University of Luebeck, Ratzeburger Allee 160, Building 67, 23562 Luebeck, Germany.ORCID 0000-0002-9883-7698
Christine KleinInstitute of Neurogenetics, University of Luebeck, Ratzeburger Allee 160, Building 67, 23562 Luebeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a complex neurodegenerative disorder that is currently incurable. As a consequence of an incomplete understanding of the etiology of the disease, therapeutic strategies mainly focus on symptomatic treatment. Even though the majority of PD cases remain idiopathic (~90%), several genes have been identified to be causative for PD, facilitating the generation of animal models that are a good alternative to study disease pathways and to increase our understanding of the underlying mechanisms of PD.

Indexed as

AnimalsBrainDisease Models, AnimalDrosophila melanogasterDrosophila ProteinsEndosomesGene Expression RegulationHumansLysosomesMetabolic Networks and PathwaysMitochondriaNerve Tissue ProteinsOxidative StressParkinson DiseaseProtein Serine-Threonine KinasesPTEN-Induced Putative KinaseDJ-1alpha protein, DrosophilaDrosophila ProteinsLRRK protein, DrosophilaNerve Tissue Proteinspark protein, DrosophilaPINK1 protein, DrosophilaProtein Serine-Threonine KinasesPTEN-Induced Putative KinaseTao protein, DrosophilaUbiquitin-Protein LigasesDrosophila melanogasterendo-lysosomal pathwaylipid homeostasismitochondriaParkinson’s disease

Identifiers

PMID33800736
PMCPMC7998316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.